Information flow through the cell (lecture 1) Flashcards

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1
Q

Mendel

A

1865 – Pea plants experiment

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2
Q

Darwin

A

1859 – Origin of species

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3
Q

Watson and Crick

A

1953

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4
Q

DNA ——> RNA

A

TRANSCRIPTION

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5
Q

RNA———> DNA

A

REVERSE TRANSCRIPTION

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6
Q

DNA ——–> DNA

A

REPLICATION

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7
Q

RNA ——–> PROTEIN

A

TRANSLATION

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8
Q

Eukaryotes

A

splicing to remove pre-mRNA
DNA—–> Pre mRNA——> mRNA
This added step increases the diversity of mRNA and proteins,
without increasing the number of genes

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9
Q

Ribosome

A

Produces polypeptide

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10
Q

Bacteria

A

DNA——> mRNA

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11
Q

Template

A

The sequence of RNA will be
identical to the DNA strand
NOT used as a template in
transcription.

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12
Q

Genetic Code

A

It is 64 codons, because there are four nucleotides
with an equal chance of being in any of the three
positions in a codon. 4x4x4 = 64
* Of the 64 triplets, 61 code for amino acids; 3 triplets
are “stop” signals to end translation
* The genetic code is redundant but not ambiguous;
no codon specifies more than one amino acid
* Codons must be read in the correct reading frame
(correct groupings) for the specified
polypeptide to be produced

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13
Q

Efficient Information Flow

A

DNA needs to simplify its structural complexity (quaternary to
primary), while proteins need to increase its complexity (primary to quaternary).

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14
Q

Evolution of the Genetic Code

A
  • The genetic code is nearly universal, shared by the
    simplest bacteria to the most complex animals
  • Genes can be transcribed and translated after being
    transplanted from one species to another
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