Inflammatory Bowel Disease Flashcards
Ulcerative colitis is found anywhere in the GI tract. True/False.
False.
UC is found only in the colon and rectum
What type of inflammation is in UC?
Mucosal
What type of inflammation is in Crohn’s disease?
Transmural/Granulomatous
What type of reaction is a food allergy?
Type 1 hypersensitivity
What immunoglobulin is involved in allergic reactions?
IgE
Is smoking protective or harmful in UC?
Protective
Is smoking protective or harmful in Crohn’s disease?
Harmful
Crohn’s disease is found anywhere in the GI tract. True/False
True.
Are skip lesions found in UC or Crohn’s?
Crohn’s
Which is more common to develop fistulae? UC or Crohn’s
Crohn’s
Symptoms of UC
DIARRHOEA & BLEEDING Increased bowel frequency Urgency Tenesmus Incontinence Night rising Lower abo pain (LIF)
Investigations for UC
CRP Albumin Plain AXR (thumb printing) Endoscopy Histology
Is is the ulceration continuous in UC?
Yes
Complications of UC
Increased risk of colorectal cancer
Toxic megacolon
Extra GI symptoms of UC
Uveitis
Rheumatoid arthritis
Skin
Symptoms of Crohn’s in the small intestine
Peri-umbilical cramps
Diarrhoea
Weight loss
Symptoms of Crohn’s disease in the colon
Lower a do cramps
Diarrhoea with blood
Weight loss
Symptoms of Crohn’s in the mouth
Painful ulcers swollen lips
Angular chelitis
Symptoms of Crohn’s in the anus
Peri-anal pain
Abscess
Blood tests for Crohn’s
CRP Albumin Platelets B12 Ferritin
Investigations for Crohn’s
Colonoscopy
Barium follow through (small bowel)
Step up treatments for UC
5ASA (mesalazine)
Steroids
Immunosuppressants
Anti-TNF therapy
Step up treatment for Crohn’s
Steroids
Immunosuppressants
Anti-TNF therapy
