Inflammatory Blistering Diseases - Westra

Question 1

What is the basic presentation of both herpes simplex 1 and 2?

Answer 1

GRoup of vesicles with red base which rapidly becomes purulent and crusted

Question 2

Describe the general difference between HSV1 and HSV2:

Answer 2

HSV 1: Primary infection usually occurs in childhood with lesions on the lips or face

HSV 2: STD of adults involving the genital area, primary infection extensive, painful vesiculations and necrosis

Question 3

What medications are normally used for herpes simplex virus?

Answer 3

acyclovir, famciclovir, and valacyclovir

HSV is recurrent lifelong disease with no cure

Question 4

Hallmark of herpes varicella?

Answer 4

Chickenpox

“dew drop on a rose petal”
fever, chills, malaise, 2-3 days before rash

Question 5

What is herpes zoster and how does it occur?

Answer 5

Shingles

Recurrence of varicella - follows nerve root to a single dermatome (painful rash)

Question 6

What does Porphyria Cutanea Tarda result from?

Answer 6

A deficiency in a heme-synthesizing enzyme

-REMEMBER - this is that one where you get hari in unusual places (hypertrichosis)

Question 7

What is it called when you have hair growing in unusual places?

Answer 7

hypertrichosis

Question 8

Hallmark of bullous pemphigoid?

Answer 8

Tense bullae on normal or erythematous skin

Question 9

Hallmark of dermatitis herpetiformis?

Answer 9

Associated with Celiac disease

Clusters of erythematous pustules, excoriations, and vesicles

Question 10

Hallmark of Pemphigus Vulgaris?

Answer 10

Flaccid Blisters everywhere

Autoimmune