Inflammation and tissue repair Flashcards
minor damage (often with overuse)
microtrauma
significant destructions (often with acute trauma)
macrotrauma
4 causes of tissue damage:
- direct trauma
- surgery
- pathology and disease processes
- problematic healing and/or presence of infection
A non-specific immune response that occurs in reaction to any type of bodily injury regardless of cause; stereotyped response that is identical and predictable regardless of causative factor
inflammation
inflammation of rapid onset and rapid resolution. The majority of the response is usually over within 12-24 hours
Acute inflammation
inflammation that is less intense but sustained over a prolonged period of time. It may be characterized by chronically elevated WBC count, low grade fever and pain
chronic
inflammation that can last for months to years, is pathological, delays healing
chronic
a local or generalized condition in which the body tissues contain an excessive amount of fluid (interstitial tissue)
edema
the presence of a microorganism that produces tissue damage.
infection
Signs and symptoms of this are similar to that of inflammation, so be aware of any acute changes in symptoms such as:
- low grade fever
- pus/drainage with foul odor
- flu-like symptoms
infection
The 4 cardinal signs of inflammation:
- heat
- erythema (redness or rubor)
- swelling
- pain
____ may be seen with extensive inflammation or in the presence of infection
fever
timeframes are ______ and will not be the same for all patients and/or injuries
general
3 stages of tissue repair:
- inflammatory response phase (0-4 days, peaking 24-72 hours post injury)
- proliferation phase (fibro-blastic repair, day 2 to 6 weeks)
- maturation (remodeling) phase (3 weeks to 2 years)
_____: one year post injury- 50-70% of normal tensile strength
ligament