Inflammation and Immunity Flashcards

1
Q

cytokine

A

small protein used in cell signaling to initiate immune response

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2
Q

which WBCs are the least abundant?

A

Monocytes (macrophages) - 3-8%
Eosinophils - 1-6%
Basophils - 0-2%

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3
Q

what is a natural killer cell?

A

lymphocyte responsible for killing virally infected cell

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4
Q

what WBCs are most abundant?

A

neutrophils - 60-80%
lymphocytes - 20-30%

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5
Q

neutrophil

A

major responder to bacterial infection

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6
Q

lymphocytes

A

major responder to viruses and fungi

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7
Q

eosinophils

A

major responder to allergies and parasitic infections

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8
Q

basophils

A

stimulate mast cells to release histamines
inflammation and allergic reaction

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9
Q

humoral/adaptive immunity cells

A

B cells
T cells

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10
Q

innate immunity cells

A

Neutrophils
macrophages

NK cells - even though this is technically a T cell, it responds non-specifically

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11
Q

antigen presenting cell

A

grab and then display antigen
producing cytokines to call other cells

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12
Q

what do B cells do?

A

produce antibodies

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13
Q

T cell differentiation

A

CD4+ cells are Th1 and Th2
CD8+ cells are cytotoxic cells

HIV targets CD4+ cells, knock out most of immune system

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