Inflammation Flashcards
Chemotaxis
the movement of cells toward or away from an area of the body in response to chemical signals
T lymphocytes and B lymphocytes
involved in antibody production
Monocytes
elevated during chronic inflammation; a source of macrophages; phagocytize microorganisms
First line of defense
skin and mucous membranes
Second and third lines
phagocytosis/inflammation, and immune system response
Specific line of defense
immune; unique/memory response
Phagocytes
Cells that ingest harmful/foreign bodies and cell debris; types are neutrophils, monocytes, and macrophages
Inflammation
Nonspecific response to conditions such as cuts, sprains, allergic reactions, caustic chemicals, extremes in temperature, foreign bodies, infection; increase blood flow to localize/remove injurious agent
Vascular response
vasodilation and increased capillary permeability for increased fluid, plasma protein products, and fibrin (to create mesh to cordon off the area
Chemical mediators
histamine and seratonin
Plasma products
globulin and antibodies
Plasma products
globulin and antibodies
Four cardinal signs
Heat and redness due to increased blood flow; swelling due to increased protein and fluid; pain due to increased pressure of fluid on nerves
Chemical mediators
histamine, serotonin, prostaglandins, leukotrienes
Pyrogens
released by leukocytes and macrophages to promote fever
Chronic inflammation
Involves lymphocytes, macrophages, and fibroblasts
Chronic inflammation
Involves lymphocytes, macrophages, and fibroblasts
Bradykinin
Released from damaged cells, activates pain receptors
Bradykinin
Released from damaged cells, activates pain receptors
Second-degree burns
Involve epidermis and part of the dermis
Third-degree burns
Involve all skin layers
Fourth-degree burns
Involve all skin layers plus underlying tissues
