Inflammation Flashcards

1
Q

Inflammation is characterised by

A
Vasodilation
Increased permeability of the capillaries
Clotting of the fluid
Migration of granulocytes and monocytes
Swelling of tissue cells
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2
Q

First Line of Defence

A

Tissue macrophage

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3
Q

Second Line of Defence

A

Neutrophil Invasion

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4
Q

Third line of Defence

A

Second Macrophage Invasion

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5
Q

Fourth Line of Defence

A

Increased production of granulocytes and monocytes by the bone marrow

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6
Q

Inflamed tissue produces factors

A

IL-1

TNF

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7
Q

IL-1 and TNF cause the increased expression of which molecules?

A

Selectin

Intercellular Adhesion Molecules

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8
Q

Effect of Adhesion molecules on neutrophils

A

They bind to the complementary proteins on the neutrophils and cause margination

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9
Q

Effect of Adhesion molecules on the endothelium

A

The intercellular attachment loosen to cause diapered is

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10
Q

Macrophages produce substances in inflammation. Name these substances

A
IL-1
TNF
GM-CSF
G-CSF
M-CSF
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11
Q

What is Pus

A

Dead macrophages and neutrophils, necrotic tissue and tissue fluid inside a cavity in the area of inflammation.

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