Inflammation

Question 1

Response of a vascularized tissue to an offending agent due to the presence of infection

Answer 1

Inflammation

Question 2

Etiology of inflammation

Answer 2

Highly due to infection

Question 3

Endogenous causes of inflammation

Answer 3

Physical agents - mechanic and thermal agents
Chemical agents
Biologic agents

Question 4

Endogenous causes of inflammation

Answer 4

Circulation disorders
Enzymes activation
Metabolic product

Question 5

Created the signs of inflammation in the 1st century AD

Answer 5

Celsius

Question 6

Four Cardinal Signs of inflammation

Answer 6

Rubor - redness
Tumor -swelling
Calor - heat
Dolor - pain

Question 7

5th sign of inflammation by Virchow

Answer 7

Functio laesa - loss of function

Question 8

3 Main Processes to release chemical mediators

Answer 8

Increased blood blow (redness and warmth)
Increase vascular permeability (swelling, pain, loss of function)
Leukocytic infiltration

Question 9

Types of inflammation (based on duration)

Answer 9

Acute
Chronic

Question 10

Types of Inflammation (based on location)

Answer 10

Local Inflammation
Systemic Inflammation

Question 11

Mechanism of Inflammation

Answer 11

Vasodilation
Exudation -edema
Emigration of cells
Chemotaxis

Question 12

Adhesion molecules

Answer 12

Selectins
Integrins
Immunoglobin Super Familyadhesion

Question 13

[Adhesion molecule] mediator for rolling phase

Answer 13

Selectins

Question 14

Types of selectins

Answer 14

E-selectin -cytokine act
P-selection - performed and stored in endothelial cells
L-selectin - expressed on surface of lymphocytes and neutrophils

Question 15

Mediator for adhesion phase, activated during the process of loose and transient adhesions between the endothelial cells leukocytes

Answer 15

Integrins

Question 16

Secreted by WBC to break down endothelial tissues

Answer 16

Collagenases