Infectious pulmonary disorders Flashcards

1
Q

What is pneumonia

A

infection within the lung
typically transmitted via inhalation, hematogenous spread or aspiration

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2
Q

what are the most common bacterial causes of pneumonia

A

streptococcus pneumoniae, H. influenzae, Mycoplasma pneumonia (walking pneumonia)

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3
Q

what is included in the lung microbiomes

A

prevoetella, veilonella and streptococcus subspecies of bacteria

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4
Q

what decreases the response to activation of irritant receptors

A

alcohol and opioids

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5
Q

what are the sxs of pneumonia

A

size/severity of disease process will yield symptoms
cough, hypoxemia, tachycardia, SOB

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6
Q

what is interstitial pneumonia

A

diffuse pattern - bacteria

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7
Q

what are the risk factors for aspiration pneumonia

A

impaired swallowing
impaired consciousness
increased chance of gastric contents reaching the lung
impaired cough reflex

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8
Q

what is mycobacteria

A

thick lipid cell wall creates waxy layer
this layer will make it more resistant to desiccation, phagocytosis, abx, dehydration
allows the bacteria to form granulomas
ex. leprocy and TB

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9
Q

how do you look for mycobacteria

A

acid fast staining

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10
Q

what does mycobacterium tuberculosis produce

A

chronic granuloma
central area full of multinucleated cells that contain TB
surrounding will be epitheloid cells

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11
Q

what is the clinical presentation of TB

A

cough
hemoptysis - alveolar damage
pleuritic pain
night sweats
fatigue
fever/chills
weight loss

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12
Q

what are the stages of TB

A

primary TB
progressive primary TB
latent phase
reactivation

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13
Q

what is miliary TB

A

bacteremic infection that spreads to other tissues
- typically via lymphatics, primarily to the lung apices, CNS, gut, skin.. all organs can be affected

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14
Q

what is bronchitis

A

inflammatory response in the lower respiratory tract
m/c associated with virus

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15
Q

what is bronchiolitis

A

inflammation of the lower airways
m/c in kids
typically viral
location will cause increase in asthma bronchconstriction

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16
Q

what is epiglotitis

A

inflammation of epiglottis
m/c d/t infection
may also be d/t thermal burns/trauma

17
Q

what is the most common pathogen with epiglotitis

A

S. aureus and S. pneumoniae

18
Q

what is the most common bronchiolitis

A

RSV

19
Q

what is the presentation of epiglotitis

A

sore throat
dysphagia
fever
dyspnea
cough
hot potato voice
stridor drooling

20
Q

what is the epiglotitis triad

A

drooling
dysphagia
distress

21
Q

what is bordetella pertussis

A

gram negative, aerobic, coccobacilli, high virulence
no known animal reservoirs
causes pertussis

22
Q

what is pertussis toxin

A

assists with binding and gaining entry to epithelial cells
causes: histamine sensitization, increased increased synthesis, promotes lymphocytes production but inhibits phagocytosis

23
Q

how is bordetella pertussis transmidited

A

inhalation or respiratory droplets (Incubation 1-3 weeks, typically 7-10 days)

24
Q

what is another name for whooping cough

A

pertusis

25
Q

nwhat are the stages of pertusis

A

catarrhal stage: 1-2 weeks
paroxysmal stage
convalescent stage