Infectious mononucleosis Flashcards
1
Q
Define infectious mononucleosis
A
clinical syndrome caused by primary EBV infection
2
Q
aetiology of infectious mononucleosis?
A
close contact (e.g. kissing, sharing eating utensils)
3
Q
epidemiology?
A
common in young people ‘kissing disease’
4
Q
classic triad of symptoms?
A
Sore throat, Pyrexia and Lymphadenopathy
also general malaise
5
Q
signs of mono?
A
- Splenomegaly
- Oedema and erythema of the pharynx
- White/creamy exudate on the tonsils
- Palatal petechiae
- Cervical/generalised lymphadenopathy
- Hepatomegaly
- Jaundice (5-10%)
6
Q
what will happen if you give someone with mono amoxicillin?
A
• Widespread maculopapular rash
7
Q
what will bloods show?
A
o FBC - leucocytosis
o LFTs - high AST/ALT
8
Q
what will a blood film show?
A
lymphocytosis with atypical lymphocytes
9
Q
gold standard test?
A
• Heterophil Antibody Test (aka Monospot Test or paul bunnell test
10
Q
management?
A
- Bed rest
- Paracetamol and NSAIDs
- Corticosteroids in SEVERE cases
11
Q
advice?
A
AVOID antibiotics
avoid contact sports for 4 weeks because of splenic rupture.
