Infectious Diseases - CNS Flashcards

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1
Q

what is the main causative agent for brain abscess

A

s viridian’s

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2
Q

what are the 3 causes of brain abscess

A

s viridian’s
norcardia asteroides
s.aureus+anerobes

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3
Q

diagnosis for brain abscess

A

CT guided aspiration, also TX

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4
Q

norcardia belongs to what family

A

actinomyces

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5
Q

inflammation of brain parenchyma is referred to as

A

encephalitis

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6
Q

encephalomyelitis

A

involves the spinal cord

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7
Q

what are the main causes of encephalitis

A

viruses!!1
HSV-1 and Flavivirus
Togaviridae and Rhabdoviridae

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8
Q

DX for encephalitis is done how

A

PCR of CSF

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9
Q

how to treat HSV-1 encephalitis

A

IV Acyclovir

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10
Q

HASV-1 mainly infects what part of the brain

A

temporal lobe so language is affected “wernicke’s aphasia”

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11
Q

which form of meningitis is usually due to virus

A

aseptic meningitis

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12
Q

what are the 2 bacteria that cause meningitis (aseptic)

A

syphillis and lyme disease

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13
Q

what are the 4 viruses that cause aseptic meningitis

A

enterovirus
coxsackie
HASV-2
echovirus

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14
Q

septic meningitis is usually due to

A

bacteria

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15
Q

acute septic meningitis in the following is caused by what

neonate

adolescents

adults

old people

diabetics

A
  1. S. agalactiae
    e. coli
    listeria monocytogenes
  2. niesseria meningitides
    s. pneumo
  3. s. pneumo
    n. meningitides
  4. s. pneumo
    listeria m.
    n. meningitides
  5. same as 4
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16
Q

kerning’s sign (meningitis)

A

lay supine, flex the hip and extend the knee of the patient and they will complain of back and hamstring pain

17
Q

brudzinskis sign (meningitis)

A

forced flexion go the head and the patient will yell in pain and flex their hips and knee “fetal position”

18
Q

main tool for diagnosis meningitis

A

Lumbar puncture

19
Q

normal opening pressure

A

70-180 ml/H2o

20
Q

normal cell count in LP

A
21
Q

normla portien LP

A

20-50mg/dL

22
Q

normal sugar in LP

A

2/3rd of blood sugar

23
Q
Aseptic (viral meningitis) LP:
pressure
cells
protein
sugar
A

> 200
25-500 (mainly lymphocytes)
50-100
2/3rd of normal blood sugar

24
Q
Bacterial Meningitis (septic)LP
pressure
cells
protein 
sugar
A

> 250
hundreds-thousands
200-500 (average 300) neutrophils

25
Q
TB meningitis LP
pressure
cells
protein
sugar
A

> 200
mainly lymphocytes
1g-6g/dL

26
Q

which kind of pneumonia will have NO Crackles heard

A

community acquired atypical pneumonia

27
Q

which pneumonia is interstitial infiltration of lymphocytes

A

atypical

28
Q

which kind of pneumonia is infiltration of neutrophils in the bronchi

A

typical

29
Q

best tx for community acquired atypical pneumonia is

A

azithromycin (macrolide) or erythromycin

30
Q

what are 6 causes of nosocomial pneumonia

A

s. aureus
p. aueriginosa
e. coli
klebsiella
enterobacter
actinobacter

31
Q

what are the two main causative agents of aspiration pneumonia

A

s. aureus and anaerobes

32
Q

what pneumonia will present with malodorous breath due to anaerobe cause

A

aspiration penumonia

33
Q

TX for aspiration penumo

A

clindamycin and ceonitin (cephalosporin)