Infectious Diseases - CNS Flashcards
what is the main causative agent for brain abscess
s viridian’s
what are the 3 causes of brain abscess
s viridian’s
norcardia asteroides
s.aureus+anerobes
diagnosis for brain abscess
CT guided aspiration, also TX
norcardia belongs to what family
actinomyces
inflammation of brain parenchyma is referred to as
encephalitis
encephalomyelitis
involves the spinal cord
what are the main causes of encephalitis
viruses!!1
HSV-1 and Flavivirus
Togaviridae and Rhabdoviridae
DX for encephalitis is done how
PCR of CSF
how to treat HSV-1 encephalitis
IV Acyclovir
HASV-1 mainly infects what part of the brain
temporal lobe so language is affected “wernicke’s aphasia”
which form of meningitis is usually due to virus
aseptic meningitis
what are the 2 bacteria that cause meningitis (aseptic)
syphillis and lyme disease
what are the 4 viruses that cause aseptic meningitis
enterovirus
coxsackie
HASV-2
echovirus
septic meningitis is usually due to
bacteria
acute septic meningitis in the following is caused by what
neonate
adolescents
adults
old people
diabetics
- S. agalactiae
e. coli
listeria monocytogenes - niesseria meningitides
s. pneumo - s. pneumo
n. meningitides - s. pneumo
listeria m.
n. meningitides - same as 4
kerning’s sign (meningitis)
lay supine, flex the hip and extend the knee of the patient and they will complain of back and hamstring pain
brudzinskis sign (meningitis)
forced flexion go the head and the patient will yell in pain and flex their hips and knee “fetal position”
main tool for diagnosis meningitis
Lumbar puncture
normal opening pressure
70-180 ml/H2o
normal cell count in LP
normla portien LP
20-50mg/dL
normal sugar in LP
2/3rd of blood sugar
Aseptic (viral meningitis) LP: pressure cells protein sugar
> 200
25-500 (mainly lymphocytes)
50-100
2/3rd of normal blood sugar
Bacterial Meningitis (septic)LP pressure cells protein sugar
> 250
hundreds-thousands
200-500 (average 300) neutrophils