INFECTIOUS DISEASES Flashcards

1
Q

VACCINES

Live Attenuated - 1

Inactivated - 2

Toxoid/Inactivated Toxin - 3

Subunit/Conjugate - 4

A
1 - BCG
      Influenza (intranasal)
      MMR
      Yellow fever
       Oral Polio/Rota/Typhoid

2 - Rabies/Influenza (I.M.)/Hepatitis A

3 - Diphtheria/Pertussis/Tetanus

4 - Pneumococcus
       Meningococcus
       Haemophilus
       Hep B
       HPV
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2
Q

Antibiotics In Respiratory System

Exacerbation of chronic bronchitis - 1

Uncomplicated CAP - 2

Atypical Pneumonia - 3

HAP - 4

A

1 - Amoxicillin/Tetracycline/Clarithromycin

2 - Amoxicillin (Doxy/Clarithro if Pen allergy; + Fluclox if staph/influenza)

3 - Clarithromycin

4 - <5d —> Co-Amox/Cefuroxime
>5d —> PIP-ZO/Ceftazidime/Ciprofloxacin

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3
Q

ANTIBIOTICS IN URINARY SYSTEM

Lower UTI - 1

Acute Prostatitis - 2

APN - 3

A

1 - TMP/Nitrofurantoin. Alt —> Amox/Cephalosporin

2 - TMP/FQ

3 - Cephalosporin/FQ

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4
Q

ANTIBIOTICS IN GENITAL SYSTEM

Gonorrhoea - 1

Chlamydia - 2

PID - 3

Syphilis - 4

Bact Vaginosis - 5

A

1 - I.M. Ceftriaxone + P.O. Azithro

2 - Doxy/Azithro

3 - M.O. (Metronidazole + Ofloxacin both P/O)/C.M.D (Ceftriaxone i.m. + Metronidazole + Doxy P/O)

4 - Benzylpenicillin/Doxy/Erythromycin

5 - Metronidazole top, po/Clinda top

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5
Q

ANTIBIOTICS IN GI SYSTEM

C. Diff - 1

Campylobacter - 2

Salmonella (non typhoid) - 3

Shigella - 4

A

1 - Metronidazole for 1st, Vancouver for subsequent

2 - Clarithromycin

3 - Cipro

4 - Cipro

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6
Q

ANTIBIOTICS IN SKIN INFECTIONS

Impetigo - 1

Cellulitis - 2

Erysipelas - 3

Animal/Human Bite - 4

Lactational Mastitis - 5

A

1 - Top Fusidic Acid —> Topical retapumulin —> Topical
Mupirocin MRSA /Oral Fluclox or Erythro if widespread

2 - Near eyes/Nose —> co-amox (PA - Clarithro + Metronidazole)
If not —> Fluclox (PA - Clarithro/Erythro/Doxy)

3 - Fluclox (PA - Clarithro/Erythro/Doxy)

4 - Co-Amox (PA - Doxy + Metro)

5 - Fluclox

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7
Q

ANTIBIOTICS IN ENT

Sinusitis - 1

Otitis Externa - 2

Otitis Media - 3

Periodontal/Periapical abscess - 4

Gingivitis - 5

Throat Infection - 6

A

1 - Amox/Doxy/Erythro

2 - Fluclox (PA - Erythro)

3 - Amox (PA - Erythro)

4 - Amox

5 - Metro

6 - Phenoxymethylpenicillin (PA - Erythro)

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8
Q

Complications of Hep B Infection

A

Fulminant Liver Failure
Chronic Hepatitis
HCC

PAN
Cryoglobulinaemia
Glomerulonephritis

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9
Q

Congenital Rubella Syndrome has the following features

________

A
Congenital cataracts
Salt &amp; Pepper Chorioretinitis
SND
Microphthalmia 
Cerebral Palsy
Growth Retardation
Purpurin skin Rash
PDA 
Hepatosplenomegaly
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10
Q

HIV OPPURTUNISTIC INFECTIONS

CD4+ 200 - 500 —> 1

CD4+ 100 - 200 —> 2

CD4+ 50 - 100 —> 3

CD4+ <50 —> 4

A

1 - Thrush/Shingles/Hairy Leukoplakia/Kaposi

2 - Toxoplasmosis/Cryptosporidiosis/Dementia/PCP/Progressive Multifocal Leukoencephalopathy (JC Virus)

3 - Aspergillosis/Candidiasis Oeso/Cryptococcal Meningitis/CNS Lymphoma

4 - CMV Retinitis/MAC inf

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11
Q

NON FALCIPARUM MALARIA

Most common form is 1)_____

1) = 2)____ , 3)___= Africa, 4)____ = Southeast Asia
5) ____ has cyclical fever of 6)___ and is subject to 7)___ due to 8)___ stage.
3) has cyclical fever of 9)___ and is associated with 10)___

Rx in Chloroquine Sensitive areas is 11)__ and that in Chloroquine resistant areas is 12)__

13) __ is avoided in pregnancy
14) ___ is given in 5) to 15)___

A

1 - P. Vivax

2 - Central America + India

3 - P.malariae

4 - P. knowlesii

5 - P.vivax/ovale

6 - 48 hrs

7 - Relapse

8 - Hypnozoite stage

9 - 72 hrs

10 - Nephrotic Syndrome

11 - Chloroquine/ACT

12 - ACT

13 - ACT

14 - Primaquine following acute Rx with Chloroquine

15 - Destroy Liver hypnozoites and prevent relapse

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12
Q

FALCIPARUM MALARIA is the 1)__ of all malaria

Rx of choice in Uncomplicated type is 2)__ and that in Severe type is 3)__

Severe Falciparum Malaria is characterised by 4)___

A

1 - Commonest

2 - oral ACT

3 - I.V. Artesunate

4 - Temp > 39
Parasite is > 2%
Schizonts on blood film
Hypoglycaemia
Acidosis
Anaemia
Complications like - Cerebral Malaria (Seizures, Coma)
ARDS
ARF (Blackwater fever secondary to IVH)
DIC
Hypoglycaemia

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13
Q

PRIMARY SYPHILIS - 1

SECONDARY SYPHILIS - 2

TERTIARY SYPHILIS - 3

CONGENITAL SYPHILIS - 4

A

1 - Painless Chancre/Non tender lymphadenopathy

2 - Maculopapular rash on trunk palms soles/Condylomata Lata/Buccaneers snail track ulcers

3 - Gumma/Ascending Aortic Aneurysm/Neurosyphilis (GPI,ARP,Tabes Dorsalis)

4 - Rhagades/Snuffles/Saddle nose/Hutchinson teeth/Mulberry Molars/Keratitis/SND/Sabre shins

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14
Q

COMPLICATIONS OF HEP C

A
Cirrhosis
HCC
Membranous GN
PCT
Cryoglobulinaemia 
Sjogren’s/Arthritis
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15
Q

ANTIBIOTICS IN MENINGITIS

Initial Empiric therapy Age 3mo - 50y —> 1

Initial Empiric therapy Age <3mo + >50y —> 2

Confirmed Meningococcal Meningitis —> 3

Confirmed Pneumococcal Meningitis —> 4

Confirmed Haemophilus Meningitis —> 5

Confirmed Listeria Meningitis —> 6

A

1 - IV Cefotaxime

2 - IV Cefotaxime + Amox

3 - IV Cefotaxime/Benzylpenicillin

4 - IV Cefotaxime

5 - IV Cefotaxime

6 - IV Amox + Genta

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16
Q

RESPIRATORY PATHOGENS

Common Cold - 1

Flu - 2

Epiglottitis - 3

Croup - 4

Bronchiolitis - 5

Bronchiectasis - 6

CAP - 7

CAP following influenza - 8

Atypical Pneumonia - 9

Pneumonia in HIV - 10

AECOPD - 11

A

1 - Rhinovirus

2 - Influenza Virus

3 - Haemophilus influenzae

4 - Parainfluenzavirus

5 - RSV

6 - Haemophilus influenzae

7 - Streptococcus pneumoniae, H.influenzae

8 - Staphylococcus aureus

9 - Mycoplasma (haemolytic anaemia/EM)/Legionella (hyponatraemia, deranged LFT)

10 - PCP

11 - Haem/Strep/Moraxella

17
Q

INFECTIOUS MONONUCLEOSIS has the following features (1)

Diagnosed by (2)

A

(1) Classic triad of

FEVER + SORE THROAT + CERVICAL LYMPHADENOPATHY (Ant + Post Triangle)

+ Other features —> Palatal Petechiae/Splenomegaly/Hepatitis/Lymphocytosis/Hemolytic Anaemia/Maculopapular,prurience rash if Amox/Amp

(2) heterophil Ab test (Monospot)

18
Q

Complications of Mycoplasma pneumoniae

A

Bulbous Myringitis
Meningo-encephalitis/GBS and other Neuro. . .
EM/EN
Hemolytic Anaemia (cold agglutinins - IgM)
Peri/Myocarditis
Hepatitis/Pancreatitis
Acute Glomerulonephritis

19
Q

Features of Legionella pneumophila

A

Flu-like symptoms + Dry Cough + Confusion + Pleural effusion + Bradycardia

Lymphopaenia + Hyponatraemia + Deranged LFT

20
Q

Causative organisms in MENINGITIS

0 - 3 mo —> 1

3 mo - 6 y —> 2

6y - 60y —> 3

> 60 y —> 4

Immunocompromised —> 5

A

1 —> GBS/E.coli/Listeria

2 —> Neisseria/Strep/Haemo

3 —> Neisseria/Strep

4 —> Strep/Neisseria/Listeria

5 —> Listeria

21
Q

TOXICITY OF ANTIVIRALS

Aciclovir - 1

Ganciclovir - 2

Ribavirin - 3

Amantadine - 4

Interferon-α - 5

Cidofovir - 6

Foscarnet - 7

A

1 - Crystalline Nephropathy

2 - Myelosuppression/Agranulocytosis

3 - Haemolytic Anaemia

4 - Confusion/Ataxia/Slurred Speech

5 - Flu-like symptoms/Anorexia/Myelosuppression

6 - Nephrotoxicity

7 - Nephrotoxicity/hypocalcaemia/hypomagnasaemia/seizures

22
Q

TOXICITY OF ANTIFUNGALS

Azoles - 1

Amphotericin B - 2

Griseofulvin - 3

Flucytosine - 4

Caspofungin - 5

A

1 - Hepatotoxicity

2 - Nephrotoxicity/Hypokalaemia/Hypomagnesemia/Flu-like symptoms

3 - Terratogenic

4 - Vomitting

5 - Flushing

23
Q

TRYPANOSOMIASIS

It is of 2 types —> 1)__ & 2)__

1) is spread via bite of 3)__ and is of 2 types —> 4)__
Early disease includes 5)__ and is treated by 6)__
Late disease includes 7)__ and is treated by 8)__

2) is caused by 9)__
Acute disease includes 10)__ and is treated by 11)__
Chronic disease includes 12)__ and is treated by 13)__

A

1 - African Trypanosomiasis/Sleeping Sickness

2 - American Trypanosomiasis/Chagas’ Disease

3 - Tsetse

4 - West African (T.gambiense) and East African (T.rhodesiense)

5 - Trypanosoma chancre (painless s/c nodule at site of inf/intermittent fever/post cervical LN enlargement

6 - IV Pentamidine/Suramin

7 - CNS Involvement

8 - IV Melarsoprol

9 - T.cruzi

10 - Chagoma (erythematous nodule at inf site)/Romana sign (unilateral periorbital edema)

11 - Azole/Nitroderivatives (benznidazole/Nifurtimox)

12 - Myocarditis —>DCM with apical atrophy + arrhythmia/Megaoesophagus —> Dysphagia/Megacolon —> Constipation

13 - Rx of complications