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MRCP 1 AMG > DERMATOLOGY > Flashcards

DERMATOLOGY Flashcards

1
Q

Guttate Psoriasis presents with 1)___, following 2)__ and is common in 3)__. Self - limiting (2-3 mo). Rx same as psoriasis.

Pityriasis Rosea presents with 4)___, followed by 5)__. It is self limiting (6 weeks).

Pityriasis Versicolor presents with 6)___, following 7)__, due to 8)__. Predisposing factors include 9)__. Rx is 10)__

A

1 - tear drop papules on back + limbs

2 - Strep inf 2-4 weeks

3 - Children and adolescents

4 - Herald patch

5 - scaly, oval, erythematous plaques along a Christmas/fir tree distribution

6 - scaly, pruritic, Hypopigmented/Pink/Brown patches on trunk

7 - suntan

8 - Malassezia furfur (fungus)

9 - Immunosuppression
Malnutrition
Cushing’s

10 - Topical ketoconazole —> If fails send skin scrapings + Oral Itraconazole

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2
Q

Psoriasis is exacerbated by 1)—

Treatment of psoriasis is as follows = 2)—

A

1= Alcohol
Trauma
Steroid withdrawal
Drugs —> ACE-I, antimalarial (chloroquine, hydroxychloroquine),
Beta-blocker, Lithium, NSAID, INFLIXIMAB

2 = 1 line —> Emollient + Topical steroid (OD) + Top Vit D (Calcipotriol/
Calcitriol/Tacalcitol) (OD) 4 weeks
2 line —> Increase Vit D to BD
3 line —> Increase steroid to BD/Coal Tar/Dithranol

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3
Q

Hereditary Haemorrhagic Telangiectasia or 1)__ is an 2)__ characterised by —> 3)__

A

1 - Osler-Weber-Rendu Syndrome

2 - AD disorder

3 - First degree relative of HHT
Epistaxis
Telangiectasia — lips/mouth/nose/fingers, Pulm/GI/Hepatic/
Cerebral/Spinal AVM

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4
Q

S/E of Isotretinoin include:-

A 
Hair thinning
Dry eyes/lips/mouth/skin
Epistaxis
ICH (with tetracycline)
Photo sensitivity
Terratogenic
Raised TG
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5
Q

Causes of Acanthosis Nigricans

A

P - PCOS, Prader Willi
C - Cushing/Cancer GI/DM/Hypothyroid/Acromegaly
O - Obesity/OCP
S - . . .

Familial
Nicotinic Acid

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6
Q

DD of Shin Lesions

Erythema Nodosum - 1

Pyoderma Gangrenosum - 2

Pretibial Myxoedema - 3

Necrobiosis Lipoidica Diabeticorum - 4

A

1 - Painful, Erythematous nodules in background of
(Sarcoidosis/IBD/Behcet’s/malignancy-Lymphoma/Pregnancy/
Inf - Strep, TB, Brucellosis/Drugs - Penicillin,OCP,Sulphonamide)

2 - Red papules —> Necrotic ulcers with violet borders in background of
(IBD/Connective tissue disorder/Myeloproliferative disorder)

3 - Erythematous lesions with shiny, orange peel skin in background of
Grave’s

4 - Shiny, yellow/red skin associated with telangiectasia in background of
DM

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7
Q

Lichen sclerosus is an 1)__ presents with 2)__ and occurs in 3)__

Lichen planus is characterised by 4)__ in 5)__

Lichenoid drug eruptions are caused by 6)__

A

1 - Inflammatory Condition

2 - Itchy, red patch in genitalia which transforms into white plaque

3 - Elderly females

4 - Pruritic Purple Polygonal Planar Papules and Plaques
Wickham’s striae —> White lines on surface
White lace pattern on buccal mucosa
Koebner’s phenomenon —> new lesions at site of trauma

5 - Palms/Soles/Flexor surfaces of arms/Genitalia

6 - Gold/Quinine/Thiazides

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8
Q

Erythema Abigne - 1

Erythema Chronicum Migrans - 2

Erythema Multiforme - 3

Erythema Nodosum - 4

A

1 - Erythematous, reticular, hyperpigmented, telangiectasic
patches after exposure to infrared radiation (fireplace/hot
bottle) —> develops into SCC

2 -

3 - Erythematous, target lesions in UL>LL, spreading to torso in
background of
C —> Cancer
A —> Autoimmune disease (Sarcoidosis/SLE)
D —> Drug (Allopurinol/OCP/Carbamazepine/Penicillin/NSAID/Nevirapine/Sulphonamide)
I —> HSV/Mycoplasma/Streptococcus

4 - Erythematous nodules in background of
(Sarcoidosis/IBD/Inf - Strep, TB, Leprosy, Coccidiomyces,
Histoplasmosis/Drugs - Penicillin,OCP,Sulphonamide)

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9
Q

Pyogenic granuloma, also called 1)__ is characterised by 2)__

A

1 - Eruptive Haemangioma

2 - small red/brown spot —> rapidly progressive, spherical lesion
(subject to bleed/ulceration) in head/neck/trunk/hands of young
adults and mouth in pregnancy

3 -

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10
Q

Acne Rosacea is characterised by 1)__, exacerbated by 2)__

Rx of choice is 3)__

A

1 - facial flushing, telangiectasia, persistent erythema with papules
and pustules, rhinophyna, blepharitis

2 - sunlight and alcohol

3 - Mild —> Topical Metronidazole
Moderate - Severe —> Oral Oxytetracycline
Predominant flushing —> Topical Brimonidine
Predominant Telangiectasia —> Laser
Supportive —> High SPF Sunscreen/Camouflage creams (redness
concealed)

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11
Q

KELOID SCAR Predisposing factors

A
  • Black, young male
  • Sternum > shoulder > neck > face > extensor surface of limbs >
    trunk
  • Incisions NOT along relaxed skin lines
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12
Q

Seborrhoea Dermatitis presents with 1)—

It may be associated with 2)—

A

1 = Itchy, scaly rash (eczematous lesions) in sebum rich areas/
face (periorbital/auricular/nasolabial folds) and scalp
distribution

2 = Otitis externa/Blepharitis/HIV/Parkinsonism

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13
Q

PELLAGRA is characterised by 1)—

It is caused by 2)— due to 3)—

A 
1 = Dermatitis (Brown scaly rash over sun exposed areas/Casal’s
       necklace if around neck)
       Diarrhoea
       Dementia
       Death
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14
Q

Malignant Melanoma has the following subtypes = 1)—

2)— variant is the most progressive.

A

1 = Superficial Spreading > Nodular > Lentigo Maligna > Acral
lentiginous

2 = Nodular

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15
Q

Slope is is of two types = Scarring and Non scarring

Scarring variant is due to 1)— and is caused by 2)—

Non scarring variant is due to 3)— and is caused by 4)—

A

1 = Destruction of hair follicles

2 = Trauma/Burn
        Tinea capitis
        Radiotherapy
        Lichen planus
        Discoid lupus

3 = Preservation of hair follicles

4 = Male pattern baldness
        Iron/Zn def
        Telegenic effluvium
        Trichotillomania
        Alopecia areata
        Drugs — OCP/Cytotoxics/Colchicine/Carbimazole/Heparin
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16
Q

Causes of YELLOW NAIL SYNDROME = 1)-

Causes of ONYCHOLYSIS = 2)-

A

1 = Bronchiectasis
Chronic sinusitis
Congenital Lymphoedema
Pleural effusion

2 = Raynaud/Dermatitis/Psoriasis
Excessive manicuring
Fungal
Hypo/Hyperthyroidism

17
Q

Actinic Keratosis is a 1)— condition caused by 2)— and presenting as 3)—

A

1 = Premalignant skin condition

18
Q

Bulbous Pemphigoid

Mainstay of Rx is 1)—

A

1 = Oral steroid

19
Q

Causes of Pruritus

A
  • CLD/CKD/Lymphoma/IDA/Polycythemia
  • Skin —> Scabies/Eczema/Psoriasis/Pityriasis Rosea/Urticaria
  • Senile Pruritus
  • DM/Pregnancy/Thyroid
20
Q

TB ASSOCIATED SKIN DISORDERS

A 
Lupus Vulgaris (COMMONEST)
Verrucosa cutis
Erythema nodosum
Scrofuloderma
Scarring alopecia
Gumma
21
Q

PREGNANCY ASSOCIATED SKIN DISORDERS

A

Pemphigoid gestationis —> Pruritic Blistering lesions starting in peri-umbilical region & spreading to trunk/back/buttock/arm —> 2nd/3rd trimester —> [Oral Steroids]

Polymorphic eruption of pregnancy —> Abd striae to Pruritic lesion —> 3rd trimester —> [Emollients -> Topical steroid -> Oral steroids]

22
Q

Molluscum Contagiosum presents with 1)—

It commonly occurs in 2)— in the following sites 3)—

A

1 = clusters of pinkish/pearly white papules with central

umbilication (diameter < 5 mm)

23
Q

DRUGS CAUSING SJS

A 
Penicillin/Sulphonamide
Allopurinol
NSAID
OCP
Phenytoin/Carbamazepine/Lamotrigine
24
Q

Systemic Mastocytosis and Carcinoid syndrome both present with 1)—

A

1 = Flushing/Abdo pain/Diarrhoea

25
Q

HYPERTRICHOSIS is 1)— hair growth and is caused by 2)—

HIRSUITISM is 3)— hair growth and is caused by 4)—

A

1 = Androgen Independent

2 = PCT
Anorexia nervosa
Minoxidil/Ciclosprin/Diazoxide
Congenital Hypertrichosis Lanuginosa/terminalis

26
Q

Eczema Herpeticum presents as 1)— with a history of 2)—

Rx of choice is 3)—

A

1 = area of worsening painful eczema + punched out erosions

2 = Atopic dermatitis/high IgE

3 = IV Aciclovir

27
Q

Zn def associated skin disorder is 1)— and is precipitated by 2)—

Other features are 3)—

A

1 = Acrodermatitis herpetiformis leading to Perioral dermatitis
(red crusted lesions) and Alopecia

2 = Malabsorption/TPN

3 = Hypogonadism/Hepatosplenomegaly/Geophagia/Short Stature/
Cognitive impairment

28
Q

ACNE VULGARIS TREATMENT ALGORITHM

A

Single Topical therapy (Benzoyl peroxide/Retinoids)

Combo Topical therapy (Benzoyl peroxide/Antibiotics/Retinoids)

Oral Antibiotics (Tetracycline — lyme/oxytetra/doxy) for max 3 mo
Erythromycin —> Pregnancy
High dose TMP —> Gram (-) folliculitis

COCP as alternative to ABx

Oral Isotretinoin

29
Q

Venous ulcers are typically seen 1)—

2)— is done in non healing ulcer to 3)—

A

1 = Above medial malleolus

2 = ABPI

3 = to assess circulation

30
Q

Scabies is caused by 1)— and is characterised by 2)—

Rx of choice is 3)—

A

1 - Mite (Sarcoptes scabiei)

2 - widespread Pruritus/linear burrows on interdigital webs,sides of
fingers, flexor aspects of wrists

3 = Permethrin 5% > malathion 0.5% (creams)
Dry & leave on skin for 8-12h (permethrin)/24h for malathion, before
washing off + repeat after 7 days

31
Q

PCT is the most common 1)—

It occurs due to deficiency in 2)— because of 3)—

A

1 - Hepatic Porphyria

32
Q

BLISTERING SKIN DISORDERS

Dermatitis Herpetiformis = 1

A

1 = Itchy vesicular lesions on extensors
Bx —> Granular deposition of IgA in upper dermis
Association —> COELIAC DISEASE
Rx —> Gluten free diet/Dapsone

MRCP 1 AMG (6 decks)

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