Infectious Diseases Flashcards

1
Q

What is the gold standard method to take neonate/infant temps?

A

rectal

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2
Q

all infants 0-29d with possible infection get what diagnostics (hint: think three locations)?

A

Urinalysis and urine culture
CBC, +/- inflammatory markers (PCT, CRP) and blood culture
Lumbar puncture and CSF culture

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3
Q

Infants 30-59d get what diagnostics?

A

Can depend on institutional guidelines
Minimum urine and blood evaluation
Based on those results and clinical presentation, consider LP

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4
Q

Infants 60-90d get what diagnostics?

A

Can depend on institutional guidelines
Minimum urine evaluation
Consider blood evaluation (10% of pyelo will have bacteremia)
Based on those results and clinical presentation, consider LP

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5
Q

under 3 months of age, who has a higher incidence of UTIs, boys or girls?

A

Boys, particularly those who are uncircumcised.

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6
Q

Risk Factors for UTI

A

Urologic abnormalities (hypospadias, vesicoureteral reflux)

Neurologic abnormalities (tethered cord, spina bifida, neurogenic bladder)

Poor hygeine (front to back!)

Sexual activity

Behavioral dysfunctional voiding

Constipation

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7
Q

What is the gold standard to Dx UTI? and what is the criteria for Dx?

A

Urine Culture

PYURIA/BACTERIURIA AND >50K COLONIES OF A SINGLE ORGANISM

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8
Q

Early UTI can suggest?

A
A GU abnormality:
Vesicoureteral reflux
Posterior urethral valves
Single/horseshoe kidney
Duplex collecting system
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9
Q

Under 2 mos of age with UTI warrants what diagnostics to be performed?

A

Renal ultrasound

Consider voiding cystourethrogram

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10
Q

2 mos to 2 years with UTI, diagnostic consideration?

A

Free pass for first UTI, then ultrasound

VCUG if ultrasound abnormal or recurrent UTIs

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11
Q

What are the most common infections in infants under 90d?

A

10% urinary tract infections/pyelonephritis
2% bacteremia
1% meningitis

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12
Q

What are the most common bacterial pathogens associated with acute otitis media?

A

SHM

Streptococcus pneumoniae
Haemophilus influenzae
Moraxella catarrhalis

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13
Q

Otitis Media Tx

A
Watchful waiting (could be viral)
Pain control
1st line- Amoxicillin
2nd line- Augmentin (Amoxicillin/Clavulanic Acid)
3rd line- Ceftriaxone IM
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14
Q

Tx for frequent/persistent otitis media infections?

A

Tympanocentesis

Myringotomy tube placement

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15
Q

Bacterial sinusitis symptoms

A

Severe nasal discharge
Persistent respiratory symptoms (>2wks)
Cough, headache, facial pressure, tooth pain, halitosis

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16
Q

Bacterial sinusitis treatment

A

watchful waiting

amoxicillin

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17
Q

which sinuses are present at birth?

A

maxillary sinus and ethmoid sinus

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18
Q

Classic symptoms of Strep Pyogenes?

A
Fever
Pharyngitis (Palatal petichiae, Tonsillar exudate, Strawberry tongue)
Tender cervical lymphadenopathy
Headache
Abdominal pain +/- vomiting
Rash
Absence of cough
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19
Q

S. Pyogenes Tx?

A

Penicillin/amoxicillin

20
Q

Bacterial Gastroenteritis Tx?

A

Rarely treated, tends to resolve without antibiotics

Antibiotics must be used cautiously, many strains can cause Hemolyic Uremic Syndrome

21
Q

S/sx of bacterial meningitis

A
Fever
Lethargy
Headache
Neck stiffness
Irritability
Vomiting
Bulging fontanelle
Petechiae
22
Q

What pathogens most commonly cause bacterial meningitis in infants <3mos.

A

E. Coli
GBS
Listeria

23
Q

What pathogens most commonly cause bacterial meningitis in older infants/children

A

Strep pneumo, Neisseria meningitis, H. Flu

24
Q

early complications of bacterial meningitis

A
Brain abscess
Subdural empyema
Seizures
SIADH
Sensorineural deafness
25
Late complications of bacterial meningitis?
developmental delay hydrocephalus epilepsy
26
URI Tx
Fluids (to prevent dehydration) Antipyretics (no ibuprofen under 6 months, no aspirin under 18 years) Nasal bulb suction or wash No definitive proof of efficacy for decongestants, expectorants, cough suppressants, against use in those <6yo. Antihistamine may give slight benefit in those over 12 months zinc, vitamin C and echinacea have limited data regarding efficacy in children; honey (>1 year) can help cough
27
hand foot mouth can sometimes also affect what area?`
diaper area
28
Roseola symptoms
Fever alone, often high, for 3-5 days | Followed by eruption of full body rash after fever gone
29
Warts Tx Options
``` salicylic acid duct tape tretinoin cream liquid nitrogen canthradin imiquimod (podophyllin) ```
30
What causes molluscum contagiosum
pox virus
31
what is the most common cause of viral encephalitis/meningitis? and which is the most serious?
most common: enterovirus most serious: HSV
32
How is HSV testing done?
by surface culture and PCR of blood/CSF
33
3 categories of HSV?
skin-eye-mouth disseminated (bloodstream, liver) CNS (meningitis, encephalitis)
34
workup for HSV meningoencephalitis?
CSF studies, includes HSV PCR vs. culture MRI EEG
35
Tx for HSV meningoencephalitis
IV acyclovir for 21 days
36
What type of HSV infection is often primary?
HSV gingivostomatitis
37
What is the cause of herpetic whitlow?
primary or recurrent HSV on the finger. Can arise after autoinoculation due to gingivostomatitis.
38
Herpetic Whitlow Sx
pain, swelling, erythema and vesicles
39
Cause of eczema herpeticum
Eczema causes weakening of the skin barrier | HSV vesicles spread rapidly and diffusely
40
Complication of eczema herpeticum
herpes keratitis
41
Treatment for Influenza
Oseltamivir = mediocre, upset stomach, use only in severe cases or hospitalized patients
42
Signs and Sx of EBV (Mono)
fever, sore throat, LAD, fatigue, splenomegaly infants-asymptomatic
43
EBV Tx
supportive, steroids if airway concern
44
All tineas can be treated topically except?
tinea capitis
45
How to treat tinea versicolor?
miconazole, clotrimazole, selenium
46
Scabies treatment
permethrin
47
Lice Tx
Permethrin shampoo for all | Mayonnaise/vaseline method