Infectious Diseases

Question 1

Dengue fever

Answer 1

Aedes astyptii. Incubation 3-14 days.

1/ Fever
2/ Abrupt fever with back pain, transitory maculopapular rash
3/ Haemorrhagic - Bleeding, Plt <100, low alb, deranged LFTs

Question 2

Malaria features

Answer 2

P falciparum <10 days - most severe disease

P vivax/ovale >21 days, benign. Rx chloroquine/hydroxy/ACT (if chloroquine R), If severe IV Artesunate.

Primaquine for anti relapse Rx 14days after chloroquine

Note no rash

Question 3

Features of schitosomia haematonbium

Answer 3

Incubation 15-20 days
Fevers, cough, urticarial rash, painless haematuria, organomegaly, lymphadenopathy

Eosinophilia. Ova detected late >50d

Rx Praziquantel

Question 4

Leptospirosis

Answer 4

Spirochete

Dx fever, myalgia, diarrhoea, conjunctival
Complicated by bleeding, jaundice, AKI, aseptic meningitis

Rx Amox, doxy, Ceftriaxone

Question 5

Typhoid fever

Answer 5

Enteric fever incubation 7-21cdays
Sx fever, abdo pain, BNO, Rose spots

Gram neg bacilli
Rx Azithro/Cipro or IV Ceft