Infectious Disease

Question 1

What treatment for latent TB resistant to Isoniazid?

Answer 1

Rifampin (4-6 months)

Question 2

What two organisms to consider in pneumonia in Cystic fibrosis patient?

Answer 2

Pseudomonas and Staph. aureus

Question 3

What antibotics are needed in treating pneumonia in cystic fibrosis patient?

Answer 3

one for MRSA

two for pseudomonas

Question 4

What CD4 level is PCP common in HIV?

Answer 4

<200/mm3

Question 5

What CXR feature does PCP have in HIV?

Answer 5

interstitial pulmonary infiltrate

Question 6

How to diagose PCP in HIV?

Answer 6

Induced sputum and bronchoalveolar lavage

Question 7

What organism to consider in osteomyelitis of SCD children?

Answer 7

salmonella

Staphy aureus

Question 8

What antibotics are needed in osteomyelitis of SCD?

Answer 8

One 3rd Gen cephalosporin for salmonella

One abx for S. aureus (MRSA vs MSSA)

Question 9

How to treat onychomycosis?

Answer 9

Oral terbinafine > oral griseofulvin

Question 10

What are 1st and 2nd line treatment of bacterial sinusitis?

Answer 10

1. Augmentin

2. Doxy or fluoroquinolones

Question 11

How to treat tinea capitis?

Answer 11

Oral terbinafine = oral griseofulvin

Question 12

What abx to treat Lyme in pregnant woman?

Answer 12

Amoxicillin

No doxy as it is bad for fetal long bone development and color discoloration

Question 13

Which lab abnormalities are associated with Rocky Mountain Spotted Fever?

Answer 13

Thrombocytopenia
Hyponatremia
Transaminitis

Question 14

What abx for fulminant C diff (e.g. HD unstable, ileus, megacolon)?

Answer 14

Metro IV and PO Vanco

Question 15

how to treat HIV associated thrombocytopenia?

Answer 15

antiretroviral

Question 16

What is Centor criteria

Answer 16

Cough (absence) + 1
Exudative tonsil +1 
LAD +1 
Temp >38 +1
Age: <14 +1; >44 -1

if more than 3, get rapid strep

Question 17

What are modes (3) of contracting Toxo in pregnant women?

Answer 17

Raw or undercook meat
unwashed produce
handling cat feces

Question 18

Sporotrichosis causes (painless or painful) papule that will soon ulcerate to drain what type of fluid? what is treatment

Answer 18

Painless
Nonpurulent, odorless fluid
Itraconazole PO 3-6 months

Question 19

What facial feature/symptoms can cat scratch disease cause? what is the rare complication?

Answer 19

conjunctivitis with ipsilateral LAD

lymph node suppuration

Question 20

What is typical presentation of PCP pneumonia in HIV?

Answer 20

when CD4 < 200

3 weeks of low grade fever and nonproductive cough

Question 21

What is typical presentation of acute HIV infection? general presentation, skin lesion, and hematology abnormality.

Answer 21

Mono like
painful mucocutaneous lesion and maculopapular rash
Leukopenia and thrombocytopenia

Question 22

what is rare sequalae of Parvovirus B19 infection in children?

Answer 22

viral arthritis (symmetrical, onset shortly after rash in face and extremities, swelling/pain/stiffness)

Question 23

What are ppx (3) for Neisseria meningitidis exposure?

Answer 23

Rifampin BID x 2
Cipro x 1
Ceftriaxone x 1

Question 24

Which infection (2) can cause stroke in young adult?

Answer 24

Vvaricella zoster virus

Meningovascular syphilis

Question 25

What to give HIV PPx? When to give?

Answer 25

Enofovir, emtricitabine, and raltegravir for 4 wk

within 72 hr

Question 26

Is it required to report HIV to partner? to local department of public health?

Answer 26

Not to partner

Yes to DPH

Question 27

Which infection can increase rate of HIV transmission?

Answer 27

Trichomonas vaginalis, motile protozoan, causes trichomoniasis.
Tx with PO metronidazole

Question 28

What virus is tested after HIV confirmation? due to antiretroviral can treat both virus.

Answer 28

Hep B