Infectious Disease Flashcards
What type of infection should you think about if a patient has been using catheters and is immunocompromised?
Candida albicans
What infectious should you think of if a patient has been on broadspectrum antibiotic therapy and is a female?
Candida albicans
Involvement of what tissue is most significant in the development of mucosal candidiasis?
esophagus
Mucosal candidiasis treatment
- Oral fluconazole
- IV voriconazole
Patient presents with pruritis in genital area, white-curdy discharge, and complaints of dyspareunia. Diagnosis?
vulvovaginal candidiasis
vulvovaginal candidiasis treatment
- Topical clotrimazole vaginal table
- Miconazole suppository
- fluconazole
Most common cause of fungal meningitis
cryptococcosis
Tools used for diagnosing cryptococcosis
- india ink
- serum antigen
Patient presents with severe headache, stiff neck, and altered mental status. History reveals the pt was taking prednisone. Diagnosis?
Fungal meningitis
Patient presents with stiff neck and severe headache after working in the garden all day. Diagnosis?
Meningitis from cryptococcus neoformans
In what type of patient may a cryptococosis infection disseminate and progress to lung disease?
-IC from HIV, long-term steroid, cancer treatment
After suspecting a patient has cryptococcosis meningitis, you do a LP and sent it to the lab. What would you order and what would you expect to find?
- Protein: increased
- Glucose: decreased
- White cells: increased lymphocytes
Cryptococcosis meningitis tx
- Amphotericin B x 14 days
- Then fluconazole x 8 weeks
Patient presents with URI after cave spelunking along the Ohio River. Likely infecting organism?
Histoplasmosis (Histoplasma capsulatum)
Primary problem with histoplasmosis infection
Respiratory illness
Presentation of histoplasmosis infection
- mild flu-like illness
- if severe: fever, cough, mild chest pain
Tx for progressive localized histoplasmosis infection
-itraconazole
Patient presents with fever, dyspnea, and nonproductive cough. You suspect pneumocystosis. What would you expect to find on CXR and ausculation?
- bilateral interstitial infiltrate (CXR)
- crackles at the base of both lungs
At what point would you decide to prophylactically treat against pneumocystosis in an AIDS patient?
When CD4 cells drop <200
Most common opportunistic infection in an AIDS patient
Pneumocystosis (pneumocystis jiroveci)
Patient presents with nonproductive cough and fever. You find an isolated increased in LDH on their lab results. Diagnosis?
Pneumocystosis
Pneumocystosis treatment
- Trimethoprim0sulfamethoxazole x 14-21 days
- Clindamycin + Primaquine
- Prednisone if PaO2 < 70mmHg
Acute rheumatic fever can follow an infection of what pathogen?
S. pyogenes (GAS)
In what patient population is acute rheumatic fever most common?
Children 5-15 years