Infectious Disease Flashcards
Vaccination schedule?
2 months - 6in1, PCV, MenB, rotavirus
4 months - 6in1, MenB, rotavirus
6 months - 6in1, PCV, MenC
12 months - MMR, MenB
13 months - HiB/MenC, PCV
Junior Infants - MMR and 4in1
First Year - HPV, Tdap and Men ACWY
What vaccines are in the 6in1?
diphtheria
tetanus
polio
pertussis
Hep B
haemophilus influenza B
What vaccines are in the MMR vaccine?
measles
mumps
rubella
What vaccines are in the 4in1 vaccine?
diphtheria
tetanus
polio
pertussis
What vaccines are in the Tdap vaccine?
tetanus
low dose pertussis
low dose diphtheria
Causes of bacterial meningitis?
children and adults -> NHS
neonates -> GBS, E coli, Listeria
Presentation of meningitis?
fever
neck stiffness
photophobia
headache
vomiting
reduced consciousness
seizures
neonates -> hypotonia, poor feeding, lethargy, irritability, hypothermia, bulging fontanelle
Special tests for meningitis?
Kernig’s test (lying on back with hip flexed and straighten knee- pain and resistance = positive)
Brudzinski’s test (lie on back and flex neck- knee and hip flexion = positive)
Mx of meningitis?
in community give stat dose of IM benzylpenicillin before transfer
ideally LP before antibiotics but don’t delay
<3 months -> amoxicillin + cefotaxime
>3months -> ceftriaxone
dexamethasone to reduce hearing loss and neuro damage
acyclovir to cover for viral
prophylaxis to close contacts -> stat dose of ciprofloxacin or rifampicin
Causes of viral meningitis?
herpes simplex virus
enterovirus
varicella zoster virus
Lumbar puncture viral vs bacterial?
bacterial cloudy, viral clear
protein high in bacterial, normal in viral
glucose low in bacterial, normal in viral
neutrophil-predominant in bacterial, lymphocyte-predominant in viral
Complications of meningitis?
sensorineural hearing loss
seizures and epilepsy
cognitive impairment and learning disability
memory loss
cerebral palsy
Most common cause of encephalitis?
viruses
bacterial and fungal v rare
Viral causes of encephalitis?
HSV (most common)
VZV
CMV
EBV
enterovirus
adenovirus
influenza
polio, mumps, rubella (always ask about vaccines)
Presentation of encephalitis?
altered consciousness
altered cognition
unusual behaviour
acute onset of focal neurological symptoms
acute onset of focal seizures
fever