Dermatology Flashcards
What is eczema?
a chronic atopic condition caused by defects in the skin barriers, leading to inflammation of the skin
Presentation of eczema?
dry, red, itchy and sore patches of skin over the flexor surfaces
Mx of eczema?
maintenance -> emollients
flares -> thicker emollients, topical steroids, wet wraps
severe flares -> systemic steroids, antibiotics
specialists -> zinc impregnated bandages, topical tacrolimus, phototherapy, methotrexate, azathioprine
Steroid ladder of topical steroids?
hydrocortisone 0.5%, 1%, 2.5%
eumovate
betnovate
dermovate
Most common opportunistic bacterial infection in eczema?
staph aureus
What is eczema herpeticum?
viral skin condition caused by HSV or VZV
usually occurs in patient with pre-existing skin condition that allows the virus to enter the skin
Presentation of eczema herpeticum?
patient who suffers with eczema develops a painful, widespread, vesicular rash
systemic symptoms such as fever, lethargy, irritability, reduced oral intake
lymphadenopathy
Mx of eczema herpeticum?
clinical diagnosis
viral swabs to confirm
acyclovir (oral or IV)
Complications of eczema herpeticum?
life-threatening, particularly in immunocompromised children
bacterial superinfection
DDx for non-blanching rash?
meningococcal septicaemia
HSP
ITP
acute leukaemias
HUS
mechanical
traumatic
viral illness
Cause of non-blanching rash?
bleeding under the skin
petechiae and purpura
Presentation of acne vulgaris?
macules
papules
pustules
comedomes
blackheads
ice pick scars
hypertrophic scars
rolling scars
Mx of acne vulgaris?
topical benzoyl peroxide
topical antibiotics
oral antibiotics (lymecycline)
COCP in females
topical retinoids
oral retinoids
Side Effects of isotretinoin?
teratogenic
dry skin and lips
photosensitivity
suicidal ideation
SJS and TEN
Examples of viral exanthemas?
measles
Scarlet fever (not viral)
rubella
Duke’s disease
Parvovirus B19
roseola infantum
Presentation of measles?
fever, coryzal symptoms, conjunctivitis
Koplik spots on buccal mucosa
rash starts on face, behind ears 5 days after fever, and spreads to rest of body
erythema, macular rash
Mx of measles?
self-resolving
isolation
notifiable disease
monitor and treat complications
Complications of measles?
pneumonia
diarrhoea
dehydration
meningitis
encephalitis
hearing loss
vision loss
death
What causes measles?
measles virus
What causes Scarlet fever?
Group A Strep (strep pyogenes)
Presentation of Scarlet fever?
red-pink, blotchy, macular, ‘sand-paper’ rash starts on trunk and spread outwards
fever
lethargy
flushed face
Strawberry tongue
sore throat
cervical lymphadenopathy
Mx of Scarlet Fever?
phenoxymethylpenicillin (penicillin V) for 10 days
notifiable disease
off school for 24hrs after starting antibiotics
Complications of Scarlet Fever?
other associated diseases with Strep A
post-streptococcal glomerulonephritis
acute rheumatic fever
What causes rubella?
rubella virus
Presentation of rubella?
erythema macular rash starting on face and spreading to rest of the body
fever
joint pain
sore throat
cervical lymphadenopathy
Mx of rubella?
supportive, self-limiting
notifiable
avoid pregnant women
school exclusion for 5 days after appearance of rash
Complications of rubella?
thrombocytopenia
encephalitis
congenital rubella syndrome to fetus in pregnant women
Other names for parvovirus B19?
fifth disease
‘slapped-cheek’ syndrome
erythema infectiosum