Infectious colitis Flashcards

1
Q

Clostridioides difficile is a Gram […] rod

A

+ve

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2
Q

Associated abx

A

Cephalosporins, PPIs, clindamycin

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3
Q

Features

A

Watery diarrhoea + raised WCC

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4
Q

Complication

A

Toxic megacolon - use abdo XR or CT

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5
Q

Mx

A

1st line - Oral vancomycin
2nd line - oral fidaxomicin
3rd line - oral vancomycin + IV metro

If severe
oral vanco + IV metronidazole

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6
Q

Diagnosis
made by detecting C. difficile […] (CD[…]) in the stool
C. difficile […] positivity only shows exposure to the bacteria, rather than current infection

A

s made by detecting C. difficile toxin (CDT) in the stool
C. difficile antigen positivity only shows exposure to the bacteria, rather than current infection

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