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Gastro and Hepatology > Alcoholic liver disease > Flashcards

Alcoholic liver disease Flashcards

1
Q

Alcoholic liver disease covers a spectrum of conditions:

alcoholic […] […] […]
alcoholic […]
[…]

A

Alcoholic liver disease covers a spectrum of conditions:

alcoholic fatty liver disease
alcoholic hepatitis
cirrhosis

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2
Q

Investigation findings in ALD

[…]-[…] is characteristically elevated
the ratio of […] to […] ratio is normally >2, a ratio of > […] is strongly suggestive of acute alcoholic hepatitis

A

gamma-GT is characteristically elevated
the ratio of AST:ALT is normally > 2, a ratio of > 3 is strongly suggestive of acute alcoholic hepatitis

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3
Q

Mx
- […] (e.g. […]) are often used during acute episodes of alcoholic hepatitis
- […]

A

Glucocorticoids, prednisolone
pentoxyphylline

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4
Q

Thiamine deficiency leads to

A

Wernicke’s Encephalopathy
- ophthalmoplegia/nystagmus, ataxia and encephalopathy

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5
Q

Investigations of wernicke’s

A

decreased red cell transketolase
MRI

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6
Q

Treat WE with

A

Thiamine (or Pabrinex)

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7
Q

If untreated

A

Wernicke-Korsakoff
- Anterograde and retrograde amnesia + confabulation

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Gastro and Hepatology (23 decks)

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