Gastro-oesophageal reflux disease

Question 1

Mx
Lifestyle interventions
- weight loss, dietary changes, elevation of the […] of the bed at night, avoidance of […]-[…] eating

• Proton pump inhibitor therapy. For patients <40 years old who present with typical symptoms and no red flags, commence treatment with a standard-dose […] for […] weeks in combination with lifestyle changes

[…] for symptomatic relief

Anti-reflux surgery for refractory cases

Answer 1

Lifestyle interventions - weight loss, dietary changes, elevation of the head of the bed at night, avoidance of late-night eating
Proton pump inhibitor therapy. For patients <40 years old who present with typical symptoms and no red flags, commence treatment with a standard-dose PPI for 8 weeks in combination with lifestyle changes
Antacids for symptomatic relief
Anti-reflux surgery for refractory cases

Question 2

Complication

Answer 2

Oesophageal ulcer
Barrett’s oesophagus
Oesophageal stricture
Adenocarcinoma of the oesophagus