Infectious Canine Hepatitis Flashcards
An uncommonly recognized disease of dogs that is caused by canine adenovirus type 1(CAV-1), a non-enveloped, icosahedral double-stranded DNA virus that is antigenically related to CAV-2
Infectious canine hepatitis(ICH)
ICH has also been referred to as
Rubarth’s disease
Infectious canine hepatitis(ICH) most commonly occurs in dogs that are less than?
1 year of age
CAV 1 is shed in?
Saliva
Feces
Urine
Initial infection of infectious canine hepatitis occurs through the
Nasopharyngeal
Conjunctival
Oropharyngeal route
ICH replicates within the
Tonsils
Infectious canine hepatitis clinical signs generally occur after an incubation period of?
4 to 9 days
ICH Overlapping disease syndrome with circulatory collapse, coma, and death after a brief illness that lasts less than 24 to 48 hours.
Peracute disease
Most commonly described syndrome, which is associated with high morbidity and reported mortality rates of around 10% to 30%.
Acute disease
Dogs with acute disease either recover or die within a
2 week period
That occurs in dogs with partial immunity, with death due to hepatic failure weeks(subacute disease) or months(Chronic infection) after initial infection.
Chronic form
Is variably characterized by the presence of fever, tonsillitis, conjunctivitis, inappetence, lethargy, weakness, polydipsia, vomiting, hematemesis, diarrhea, cough, tachypnea, and icterus.
Acute disease
Occurs in the first week of illness and results from replication of virus within corneal endothelial cells
Cornelia edema(blue eye)
Glomerulonephritis usually occurs about
1 to 2 weeks
Glomerular lesions contain deposits of viral antigen
IgG
IgM
C3
Infection of the glomerular endothelium is followed by a
Persistent tubular infection
Development of interstitial nephritis and viruria
ICH Viral shedding in the uterine can occur for up to _ after infection.
6 to 9 months
Persistent corneal edema fails to resolve for months and may be associated with complications such as
Glaucoma
Reportedly susceptible to ICH complication
Afghan hound
Puppies with CAV-1 encephalitis may show signs of:
Circling
Vocalization
Head pressing
Ataxia
Blindness
May be manifested as cutaneous or mucosal petechial hemorrhages; epistaxis; or prolonged bleeding from venipuncture sites.
Coagulopathies
