Canine Distemper Flashcards
A relatively large(150-250nm) single stranded RNA virus with a lipoprotein envelope
Canine Distemper
Diseases caused by members of the Morbillivirus genus:
Measles in primates
Rinderpest in Artiodactyls
Peste des petit ruminants in small ruminants
Three recently discovered viruses
Phocine distemper virus in seals
Cetacean Morbillivirus in porpoises and dolphins
Most common source of infection in
Direct contact between the susceptible dog
Incubation period of CDV
1 week- 1 month
Canine distemper is highly contagious, and viral shedding may follow infection for
60-90 days
Canine distemper virus usually enters via the
Epithelium of the upper respiratory tract
CDV multiplies in?
Macrophages
CDV Spreads to?
Tonsils and regional lymph nodes
CDV viral replication can occur within
2 to 4 days post infection
Within a week, CDV proliferates in lymphoid organs such as
Spleen
Mesenteric lymph nodes
Kupffer’s cells in the liver
Lamina propria in stomach and small intestine
Are associated with viral spread due to loss of T and B cells.
Fever and leucopenia
If there is inadequate immune response, severe clinical signs of CDV is seen at
2-3 weeks with death by 3-4 weeks
Dogs that recover from CDV can shed virus for
2-3 months
Dogs that recover from CDV can shed virus for
2-3 months
The pathogenesis within _ days depends on the humoral and cell mediated host immune response.
9-14 days
Dogs with the neurologic disease may develop _ of the footpads and nose as a result of epithelial damage cause by the virus.
Hyperkeratosis
This manifestation in dogs gave rise to the term _ as an alternative common name for canine distemper.
Hardpad disease
CDV infection are modulated by
Viral virulence
Environmental conditions
Hostage
Immunity
A neurologic manifestation of CD may occur _ weeks after recovery from acute generalized infection.
1-3
The involuntary twitching of muscles in the forceful simultaneous contraction
Myoclonus
Treatment for CDV
Broad spectrum antibiotics
Balance electrolyte solutions
Parenteral nutrition
Antipyretics
Analgesics
Anticonvulsants
Good nursing care
