Infections-side effects Flashcards
Drugs that cause ototoxicity? (3)
1) Aminoglycosides e.g gentamicin, steptomycin etc
2) Glycopeptides e.g vancomycin, teicoplanin etc
3) Macrolides e.g erythromycin etc
Drugs that cause renal impairment? (2)
1) Aminoglycosides
2) Glycopeptides
Drugs that cause hepatic impairment? (7)
1) Macrolides
2) Flucloxacillin (cholestatic jaundice)
3) Co-amoxiclav (Cholestatic jaundice)
4) Nitrofurantoin (hepatitis)
5) Tetracylines (hepatotoxicity)
6) Clindamycin (jaundice)
7) Monoflaxacin (life-threatening hepatotoxicity)
Drugs that cause tendon rupture?
Quinolones e.g ciproflaxacin, monoflaxacin etc
Drugs that cause skin photo-sensitivity?
1) Tetracyclines
2) Quinolones
Antibiotic that impairs driving?
Ciproflaxacin
Antibiotic that can cause ‘red man syndrome’?
Vancomycin
Antibiotics that are teratogenic? (3)
1) Trimethoprim, Co-trimazole
2) Aminoglycosides (ear damage)
3) Tetracylines (deposits in bones)
Antibiotics that cause blood disorders? (2)
1) Trimethoprim, co-trimazole
2) Glycopeptides
Drugs that cause esophageal irritation?
1) Tetracylines
2) Clindamycin
Antibiotic that can cause a hypertensive crisis and why?
Linezolid- it is an MAOI
Antibiotics that can cause CNS toxicity?
Penicillins
Antibiotics that can cause visual disturbance? (2)
1) Tetracylines- STOP
2) Metronidazole (optic neuropathy-REPORT)
Antibiotics that prolong the QT interval? (2)
1) Quinolones
2) Macrolides
CYP450 inhibitors?
Macrolides e.g erythromycin, clarithromycin etc
