Infection Pathology Flashcards

1
Q

Endotoxin

A

Feature of gram negative bacteria
0 LPS, Lipid A (anchors LPS)
Pathogenic in high levels

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2
Q

Exotoxins

A

Proteases, hyaluronidases, coagulates, fibrinolysins
Toxins
Neurotoxins
Superantigens - stimulate T lymphocytes —> proliferation and cytokines release

Pseudo has significant exotoxin

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3
Q

Gram positive wall structure

A

15-50nm thick - 50% peptidoglycan, acidic polymer 5-10% proteins and polysaccharides

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4
Q

Gram negative wall

A

More complex,
Periplasmic space
Peptidoglycan layer 2nm thick
Complex polysaccharides (endotoxin)

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