Infection, Immunology and Allergy Flashcards
how many children with RSV bronchiolitis require hospitalisation
1-3%
SCID
genetic mutations which lead to an absence of T and B cell function (usually AR)
ADA deficiency (loss of purine salvage) accounts for 10-15% - X linked
present with recurrent life threatening infections
present 6-7 months
treatment: ABx, stem cell transplant and gene therapy
Lymphopenia and hypogammaglobulinaemia
What type of cells are absent in Di George syndrome
T lymphocytes
due to maldevelopment of thymus
common variable immunodeficiency
history of invasive bacterial infections
numerous immune system abnormalities
autoimmune complications
most common cause meningitis in neonate
group b strep
e coli
listeria
abx for meningitis in neonate
cefotaxime and amoxicillin
what kind of organism is E.coli
gram neg
Streptococcus pneumonia
gram pos
common cause meningitis in older children
starts with fever and headache
what life cycle stage occurs with Plasmodium vivax as opposed to plasmodium falciparum infection
hypnozoites
Staph aureus enterotoxin
vomiting and non bloody diarrhoea
diarrhoea usually watery and begins few hours after vomiting
after inadequately reheated food, pre made salads, contaminated meats or dairy
Salmonella typhi
high fever, diarrhoea, travel abroad
rose salmon rash
treat with ceftriaxone
Rotavirus
most common cause of viral diarrhoea
infant attending nursery
profuse watery stools, vomiting, low grade fever
treatment of MRSA
rifampicin and vancomycin
babies born to mothers who develop chicken pox 7 days before - 7 days after birth management:
VZOG regardless of serological status
C1, C2,C4 deficiency associations
associated with SLE and RA
C2: and recurrent URTI with strep pneumoniae
C4: hereditary angioedema
