Diabetes

Question 1

lipids in diabetic patient

Answer 1

normal LDL
low HDL
elevated triglycerides

can be reversed if good control

Question 2

how often should insulin pump site be changed

Answer 2

every 2-3 days

Question 3

MODY2 aka Glucokinase receptor mutation

Answer 3

incidental finding hyperglycaemia at diagnosis
mildly rasied OGTT and fasting glucose
very little deterioration in glycaemia with age
AD
little or no response to insulin or meds

Question 4

what protein do Sulphonylureas e.g. gliclazide act on

Answer 4

ATP sensitive K channel
SE: hypoglycaemia and weight gain

Question 5

diabetes inspidius

Answer 5

polyuria, polydipsia, increased frequency, nocturnal enuresis
nephrogenic: urine concentration remains the same following administration of DDAVP, due to insensitivity to ADH