Infection and Immunity Meds Flashcards

1
Q

Cephalosporins Pregnancy category

A

B

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2
Q

What medicine has 5 generations

A

cephalosporins

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3
Q

Cephalosporins Side Effects

A

N/V/D, superinfection, dizziness

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4
Q

Cephalosporin Uses

A

e. coli and proteus mirabilis

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5
Q

If a patient is allergic to penicillin they are probably allergic to…

A

cephalosporins

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6
Q

What should you never give cephalosporins with

A

tetracycline

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7
Q

Cephalosporins nursing considerations

A

check renal and kidney fx, caution with kidney disease and monitor bleeding if taken with an anticoag

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8
Q

Tetracyclines Pregnancy Catergory

A

D!!!

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9
Q

Tetracyclines MOA

A

bacteriostatic

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10
Q

Tetracycline Uses

A

Lyme disease, acne, STD

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11
Q

Tetracycline Side Effects

A

photosensitivity, N/V/D

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12
Q

Tetracyclines Nursing Consideration

A

not for kids under 8, take with a meal, no dairy or antacids`

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13
Q

Fluoroquinolone Pregnancy Catergory

A

C

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14
Q

Fluoroquinolone MOA

A

stops synthesis of bacterial DNA

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15
Q

Fluoroquinolone Uses

A

S. Epidermis, UTI, Anthrax, respiratory infection

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16
Q

Fluoroquinolone Side Effects

A

Photosensitivity, Fatigue, Urine Crystals, Peripheral Neuropathy, Tendonitis, Tendon rupture

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17
Q

What happens when flurorquinolones are taken with NSAIDS

A

high risk for CNS stimulation

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18
Q

What happens when admiadarone is taken with flurorquinolones

A

Prolonged QT intervals

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19
Q

Fluoroquinolone Nursing Considerations

A

check renal fx, no antacids or dairy

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20
Q

Sulfonamides Pregnancy Category

A

D!

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21
Q

Sulfonamides MOA

A

stops bacteria from synthesizing folic acid, bacteriostatic

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22
Q

Sulfonamides Uses

A

UTI, ear infection, pneumonia, prophylaxis AIDS

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23
Q

Sulfonamide SE

A

decreased blood count, photosensitivity, urine crystals, N/V/D

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24
Q

Sulfonamide Contraindications

A

CHF, Renal Failure

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25
Q

Sulfonamide Nursing Considerations

A

drink 3000 ml of water daily, no antacids, check kidney and renal fx

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26
Q

Metronidazole Pregnancy Category

A

D!

27
Q

Metronidazole Uses

A

GI infections, prophylaxis for surgery (H. Pylori, IBD)

28
Q

Metronidazole Side effects

A

GI Distress, dark urine, dry mouth, depression, metallic taste, paresthesia, seizures

29
Q

Metronidazole Nursing consideration

A

NO AOLCHOL

30
Q

Carbapenems MOA

A

inhibits cell membrane synthesis, bactericidal

31
Q

Carbapenems Uses

A

strep, staph, proteus mirabilis

32
Q

Carbapenems Contraindications

A

seizures
meningitis
advanced kidney disease

33
Q

Carbapenems SE

A

CNS effects, N/V/D

34
Q

Glycopeptides Uses

A

Staph, MRSA, Gram +

35
Q

Glycopeptides Nursing Considerations

A

give slowly IV, check kidney FX

36
Q

Glycopeptides SE

A

redman syndrome, nephrotoxicity, ototoxicity

37
Q

Vancomycin

A

glycopeptide, can cause C.diff if given IV, but treatment for c.diff is oral vancomycin

38
Q

Penicillin MOA

A

stops synthesis of bacterial cell wall; bactericidal and bacteriostatic

39
Q

Penicillin SE

A

rash

40
Q

what is commonly used as a combo drug with penicillin

A

clavulanate- which stops breakdown of antibiotic

41
Q

Penicillin Nursing Considerations

A

dont give within 1 hour of aminoglycerides, decreases birth control, check renal and kidney fx

42
Q

Lincosamides MOA

A

affects protein synthesis within bacterial nucleus

43
Q

Lincosamides Uses

A

strep, C. diff, gonorrhea

44
Q

Lincosamides SE

A

bone marrow suppression (decreased blood count)

45
Q

Macrolides MOA

A

alters protein synthesis within cell; bacteriostatic and bactericidal

46
Q

Macrolides Uses

A

strep, c. diff and gonorrhea

47
Q

What can be given in place of penicillin

A

macrolides

48
Q

Macrolides SE

A

superinfection, allergy, confusion, liver issue

49
Q

Macrolides Nursing Considerations

A

check liver fx, no grapefruit or dairy, decreases birth control effectiveness

50
Q

Aminoglycerides MOA

A

bactericidal

51
Q

Aminoglycerides Side effects

A

OTOTOXICITY, NEPHROTOXICITY, cramps, tremors, photosensitivity, liver issues, vertigo, tinnitus

52
Q

Aminoglycerides Nursing Considerations

A

give hour apart from penicillins, pregnancy category D, OTOTOXICITY IF GIVEN W DIURETICS

53
Q

What aminoglyceride should we check peak and through of?

A

gentramicin

54
Q

What bacteria causes TB

A

mycobacterium tuberculosis

55
Q

Antitubercular Drugs SE

A

Orange urine, neuropathy, low blood count, ototoxicity, nephrotoxicity

56
Q

Prophylaxis TB treatment for people who were exposed

A

Isoniazid (INH)

57
Q

Antitubercular Drugs Nursing considerations

A

take on empty stomach, decreases Birth control, check kidney and liver fx

58
Q

Antitubercular 1st line drugs

A

isoniazid and ritampin

59
Q

Antifungal Side effects

A

chills, hypotension, flushing, nephrotoxicity, electrolyte imbalance

60
Q

Antifungal nursing considerations

A

check kidney and liver fx; inhibits metabolism of other drugs

61
Q

Antivirals side effects

A

neuro problems, INCREASED BLEEDING TIME, DECREASED BLOOD COUNT, malaise, GI disturbances

62
Q

Antiviral Nursing considerations

A

check liver and kidney fx

63
Q

Vaccine SE

A

anaphylaxis, soreness, fever

64
Q

Vaccine Nursing Considerations

A

dont give to immunocompromised, check for egg allergy