Infection and Immunity Meds Flashcards

1
Q

Cephalosporins Pregnancy category

A

B

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2
Q

What medicine has 5 generations

A

cephalosporins

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3
Q

Cephalosporins Side Effects

A

N/V/D, superinfection, dizziness

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4
Q

Cephalosporin Uses

A

e. coli and proteus mirabilis

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5
Q

If a patient is allergic to penicillin they are probably allergic to…

A

cephalosporins

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6
Q

What should you never give cephalosporins with

A

tetracycline

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7
Q

Cephalosporins nursing considerations

A

check renal and kidney fx, caution with kidney disease and monitor bleeding if taken with an anticoag

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8
Q

Tetracyclines Pregnancy Catergory

A

D!!!

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9
Q

Tetracyclines MOA

A

bacteriostatic

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10
Q

Tetracycline Uses

A

Lyme disease, acne, STD

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11
Q

Tetracycline Side Effects

A

photosensitivity, N/V/D

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12
Q

Tetracyclines Nursing Consideration

A

not for kids under 8, take with a meal, no dairy or antacids`

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13
Q

Fluoroquinolone Pregnancy Catergory

A

C

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14
Q

Fluoroquinolone MOA

A

stops synthesis of bacterial DNA

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15
Q

Fluoroquinolone Uses

A

S. Epidermis, UTI, Anthrax, respiratory infection

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16
Q

Fluoroquinolone Side Effects

A

Photosensitivity, Fatigue, Urine Crystals, Peripheral Neuropathy, Tendonitis, Tendon rupture

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17
Q

What happens when flurorquinolones are taken with NSAIDS

A

high risk for CNS stimulation

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18
Q

What happens when admiadarone is taken with flurorquinolones

A

Prolonged QT intervals

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19
Q

Fluoroquinolone Nursing Considerations

A

check renal fx, no antacids or dairy

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20
Q

Sulfonamides Pregnancy Category

A

D!

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21
Q

Sulfonamides MOA

A

stops bacteria from synthesizing folic acid, bacteriostatic

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22
Q

Sulfonamides Uses

A

UTI, ear infection, pneumonia, prophylaxis AIDS

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23
Q

Sulfonamide SE

A

decreased blood count, photosensitivity, urine crystals, N/V/D

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24
Q

Sulfonamide Contraindications

A

CHF, Renal Failure

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25
Sulfonamide Nursing Considerations
drink 3000 ml of water daily, no antacids, check kidney and renal fx
26
Metronidazole Pregnancy Category
D!
27
Metronidazole Uses
GI infections, prophylaxis for surgery (H. Pylori, IBD)
28
Metronidazole Side effects
GI Distress, dark urine, dry mouth, depression, metallic taste, paresthesia, seizures
29
Metronidazole Nursing consideration
NO AOLCHOL
30
Carbapenems MOA
inhibits cell membrane synthesis, bactericidal
31
Carbapenems Uses
strep, staph, proteus mirabilis
32
Carbapenems Contraindications
seizures meningitis advanced kidney disease
33
Carbapenems SE
CNS effects, N/V/D
34
Glycopeptides Uses
Staph, MRSA, Gram +
35
Glycopeptides Nursing Considerations
give slowly IV, check kidney FX
36
Glycopeptides SE
redman syndrome, nephrotoxicity, ototoxicity
37
Vancomycin
glycopeptide, can cause C.diff if given IV, but treatment for c.diff is oral vancomycin
38
Penicillin MOA
stops synthesis of bacterial cell wall; bactericidal and bacteriostatic
39
Penicillin SE
rash
40
what is commonly used as a combo drug with penicillin
clavulanate- which stops breakdown of antibiotic
41
Penicillin Nursing Considerations
dont give within 1 hour of aminoglycerides, decreases birth control, check renal and kidney fx
42
Lincosamides MOA
affects protein synthesis within bacterial nucleus
43
Lincosamides Uses
strep, C. diff, gonorrhea
44
Lincosamides SE
bone marrow suppression (decreased blood count)
45
Macrolides MOA
alters protein synthesis within cell; bacteriostatic and bactericidal
46
Macrolides Uses
strep, c. diff and gonorrhea
47
What can be given in place of penicillin
macrolides
48
Macrolides SE
superinfection, allergy, confusion, liver issue
49
Macrolides Nursing Considerations
check liver fx, no grapefruit or dairy, decreases birth control effectiveness
50
Aminoglycerides MOA
bactericidal
51
Aminoglycerides Side effects
OTOTOXICITY, NEPHROTOXICITY, cramps, tremors, photosensitivity, liver issues, vertigo, tinnitus
52
Aminoglycerides Nursing Considerations
give hour apart from penicillins, pregnancy category D, OTOTOXICITY IF GIVEN W DIURETICS
53
What aminoglyceride should we check peak and through of?
gentramicin
54
What bacteria causes TB
mycobacterium tuberculosis
55
Antitubercular Drugs SE
Orange urine, neuropathy, low blood count, ototoxicity, nephrotoxicity
56
Prophylaxis TB treatment for people who were exposed
Isoniazid (INH)
57
Antitubercular Drugs Nursing considerations
take on empty stomach, decreases Birth control, check kidney and liver fx
58
Antitubercular 1st line drugs
isoniazid and ritampin
59
Antifungal Side effects
chills, hypotension, flushing, nephrotoxicity, electrolyte imbalance
60
Antifungal nursing considerations
check kidney and liver fx; inhibits metabolism of other drugs
61
Antivirals side effects
neuro problems, INCREASED BLEEDING TIME, DECREASED BLOOD COUNT, malaise, GI disturbances
62
Antiviral Nursing considerations
check liver and kidney fx
63
Vaccine SE
anaphylaxis, soreness, fever
64
Vaccine Nursing Considerations
dont give to immunocompromised, check for egg allergy