Infection

Question 1

Factors to consider when administering Anti-Virals?

Answer 1

• Anti-viral meds are generally very specific to particular viral infections, but generally based in inhibiting replication as oppose to cell lysis.
• Difficult to kill all virus.
• Allergic Rx to specific med is the main concern are the main concern and fair

Question 2

Common Side effects of Antibiotic therapy

Answer 2

• Predisposes for C difficile
• Disrupts natural flora and fauna in GI (diarrhea, abd pain, L/O appetite, nausea, vomiting)
• Vaginal yeast infections
• Hepatic toxicity
• Nephrotoxicity

Question 3

Why are viruses difficult to treat?

Answer 3

They remain inside eukaryote cell. Dangerous to target self-cell.

Question 4

LIfespan considerations for antibiotic therapy (Peds, Elderly, Pregnancy) Hint- Similar to all lifespan concerns

Answer 4

• Pediatric- Dosage by weight
• Elderly- lower dosages (decline in organ functions), polypharmacy, GI sensitivities, susceptible host (immune compromised)
• Pregnancy- potential harm to fetus and mother

Question 5

Common side effects of Antibiotics?

Answer 5

• Nausea, vomiting, diarrhea

* Neprho and hepatic toxicity

Question 6

When are antibiotics used as a prophylactic

Answer 6

Pre or Post op for prevention of infection

Question 7

Empirical use of Antibiotic

Answer 7

Doc uses clinical judgement to guess most likely bacteria causing infection before C& S can verify. Generally broad spectrum antibiotics are used.

Question 8

What is a Superinfection?

Answer 8

Infection that comes abbot during tx of another primary infection and often resistant to past infection antibiotics
• C Difficile being the common example