Infection Flashcards
what are 5 populations that are at increased risk for sepsis
older adults, immunosuppression, chronic illness, undergoing surgery, malnutritin
explain the pathophysiology of sepsis
microorganism invade the body tissues which causes an immune response. this leads to capillary instability and vasodilation. this leads to a widespread inflammatory response called systemic inflammatory response syndrome. cytokines will also activate the coagulation system leading to blood clots. this can occlusions of blood vessels
what criteria defines SIRS (temp, wbc count, heart, breathing)
temp: above 38.3 or below 36
wbc: greater than 12000 cells/mm3, less than 4000 cells/mm3, or greater than 10% immature wbc (bands)
tachycardia
tachypnea
explain the evolution of symptoms in the case of septic shock (bp, heart rate, body temp, respiratory rate, urine output)
- bp is normal or hypotensive with response to fluids. bp later does not respond to fluids
- heart rate increases
- hyperthermia, fever, and bounding pulses. later body temp drops and skin becomes cool
- respiratory rate is elevated
- urine output may be normal. later urine output decreases
how is sepsis corrected/what measures can be taken to reduce the chances of mortality
rapidly identify the source of infection, reestablish tissue perfusion through use of fluids, broad spectrum antibiotics until a culture is received, sedation, enteral or parenteral feedings
what is neurogenic shock
vasodilation occurs due to an imbalance between parasympathetic and sympathetic stimulation
what does neurogenic shock do to an individuals in terms of bp, hr, and skin appearance
bp: hypotension
hr: bradycardia
skin: dry and warm
what are 4 causes of neurogenic shock
spinal cord injury, spinal anesthesia, nervous system damage, depressant action of medications
what is important for the nurse to do in terms of bed positioning when the patient is receiving spinal or epidural anesthesia
maintain the head of the bed at at least 30 degrees
what must the nurse continually assess for in the case of neurogenic shock in terms of the peripheral vascular system
VTE. signs to watch for includes pain, redness, tenderness, and warmth
what are the 3 defining characteristics of anaphylaxis
- acute onset
- the presence of two or more symptoms: respiratory compromise, hypotension, gi distress, skin or mucosal irritation
- cardiovascular compromise
what are 6 symptoms of anaphylaxis
headache, lightheadedness, nausea, vomiting, abdominal pain, pruritus
what are 5 manifestations of severe c. diff
watery diarrhea 10-15 times a day, severe abdominal pain, tachycardia, fever, increased white blood cell count
when do signs and symptoms of c. diff commonly occur
5-10 days after starting antibiotics
what is first line treatment for mods (multi organ dysfunction syndrome)
oxygen, fluids, vasopressors, anitbiotics