Induction agents Flashcards
1
Q
What aspect of PRIS causes arrhythmia
A
FFA anf acyl-acetate
2
Q
What aspect of PRIS causes renal failure
A
ATP depletion
Muscle necrosis
Rhadbo
3
Q
What is propofol emulsion made up of
A
Egg lecithin
soya bean oil
disodium edetate
4
Q
Propofol
VOD, Clearance, protein binding and elimination
A
4L. clearance = 30-60ml/kg/min
elimination half life = 5-12 hours
98% protein bound
4
Q
What enzymes metabolise propfol
A
Glucuronosyltransferase
CYP450
4
Q
Products of propofol metabolism
A
2,6,diisopropylbenzoquinone
4, hydroxypropofol
5
Q
A
