Inducers And Inhibtors Flashcards
What is the mechanism of action of an inducer?
An inducer increases the activity of drug-metabolizing enzymes, leading to faster metabolism of drugs.
True or False: Inducers decrease the effectiveness of medications.
True
Which enzyme system is commonly affected by inducers?
Cytochrome P450 system
What is the general effect of an inducer on drug levels in the body?
Decreases drug levels
What is the mechanism of action of an inhibitor?
An inhibitor decreases the activity of drug-metabolizing enzymes, leading to slower metabolism of drugs.
True or False: Inhibitors increase the effectiveness of medications.
True
Which enzyme system is commonly affected by inhibitors?
Cytochrome P450 system
What is the general effect of an inhibitor on drug levels in the body?
Increases drug levels
Which type of drug interaction is more likely to cause toxicity: an inducer or an inhibitor?
Inhibitor
What is the term for the process where an inducer increases the metabolism of another drug?
Induction
What is the term for the process where an inhibitor decreases the metabolism of another drug?
Inhibition
Which class of medications are commonly used as inducers?
Anticonvulsants
Which class of medications are commonly used as inhibitors?
Antidepressants
What is the primary concern when considering drug interactions with inducers and inhibitors?
Therapeutic efficacy and safety
What is the key role of PMHNPs in managing patients taking medications affected by inducers and inhibitors?
Monitoring for drug interactions and adjusting medication doses as needed
