Indirect-Acting Cholinergic Agonists

Question 1

What is the function of indirect-acting cholinergic agonists?

Answer 1

It is a cholinesterase inhibitor drug that binds with cholinesterase, allowing acetylcholine to activate the muscarinic and nicotinic cholinergic receptors

Question 2

By inhibiting cholinesterase, what exactly happens?

Answer 2

This action permits skeletal muscle stimulation, which increases the force of muscular contraction.

Question 3

How are cholinesterase inhibitors helpful? To whom?

Answer 3

They are useful in increasing muscle tone for clients with myasthenia gravis

Question 4

Besides increasing muscle contractility, what else can cholinesterase inhibitors stimulate?

Answer 4

Increase GI motility, bradycardia, miosis, bronchial constriction, and increased micturition (increased urination).

Question 5

Other than myasthenia gravis, what other health problems do indirect-acting cholinergic agonists treat?

Answer 5

Glaucoma, Alzehimer’s disease, and muscarinic antagonist poisoning

Question 6

There are two types of indirect-acthing cholinesterase inhibitors, what are they?

Answer 6

Reversible and irreversitble cholinesterase inhibitors