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Drugs List Phase 3 > Indication --> Drug > Flashcards

Indication --> Drug Flashcards

1
Q

Dyspepsia

A

Aluminium and Magnesium Hydroxide with Calcium Carbonate

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2
Q

Heartburn

A

Aluminium and Magnesium Hydroxide with Calcium Carbonate

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3
Q

Gastric Reflux

A

Sodium Alginate with NaHCO

Omeprazole (PPI)

Lansoprazole (PPI)

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4
Q

Stomach Ulcer

A

Ranitidine (H2- Antagonist)

Cimetidine (H2 - Antagonist)

Omeprazole (PPI)

Lansoprazole (PPI)

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5
Q

Duodenal Ulcer

A

Omeprazole (PPI)

Lansoprazole (PPI)

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6
Q

Pancreatic Insufficiency

A

Pancreatin (Enzymes)

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7
Q

Cystic Fibrosis

A

Pancreatin (Enzymes)

Dornase Alfa (Mucolytic)
Carbocisteine (Mucolytic)
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8
Q

Pancreatitis

A

Pancreatin (Enzymes)

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9
Q

Constipation

A

Methylcellulose (Bulk)

Isphagula Husk (Bulk)

Docusate (Softener)

Arachis Oil (Softener)

Macrogol (Osmotic)

Lactulose (Osmotic)

Mg Sulphate (Osmotic)

MgOH (Osmotic)

Bisacodyl (Stimulant)

Senna (Stimulant)

Picosulfate (Stimulant)

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10
Q

Diarrhoea

A

Loperamide (Opioid Anti Motility)

Codeine (Opioid Anti Motility)

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11
Q

Left Ventricular Heart Failure

A

Furosemide (decrease BP)

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12
Q

Oedema

A

Furosemide

Bendroflumethiazide

Spironolactone

Epleronone

Amiloride

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13
Q

Hypertension

A 
THIAZIDES
Indapamide
Bendroflumethiazide
Chlorthalidone
Hydrochlorothiazide 
ACEi
Ramipril
Captopril
Perindopril
Lisinopril
ARBs
Losartan
Valsartan
Irbesartan
Candesartan

Renin Inhibitor - Aliskiren

B BLOCKERS
Bisoprolol
Atenolol
Metaprolol
Propranolol
Labetalol

A-1 BLOCKER
Doxazosin

A-2 Agonist
Clonidine

CCB
Amlodipine
Nifedipine
Diltiazem

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14
Q

Congestive Heart Failure

A

POTASSIUM SPARING
Spironolactone
Eplerenone
Amiloride

Digoxin (Cardiac Glycoside)

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15
Q

Cerebral Oedema

A

Mannitol

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16
Q

Intra-Ocular Pressure

A

Mannitol (Osmotic)

Acetazolamide (CAi)

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17
Q

Open and Acute Closed Angle Glaucoma

A

Acetazolamide (CAi)

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18
Q

Diabetic Nephropathy

A 
ACEi 
Ramipril
Captopril
Perindopril
Lisinopril
ARBs
Losartan
Valsartan
Irbesartan
Candesartan

Decrease Vasocontriction and lower BP

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19
Q

Heart Failure

A 
ACEi
Ramipril
Captopril
Perindopril
Lisinopril
ARBs
Losartan
Valsartan 
Irbesartan
Candesartan

Ivabradine

GTN
ISMN

Sacubitril (Neprilysin Inhib) with ARB For reduces EF

NITRATES
GTN
ISMN

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20
Q

Stable Angina

A

B BLOCKER
Bisoprolol
Atenolol
Propranolol

CCB
Amlodipine
Nifedipine
Diltiazem

Ivabradine (normal sinus)

ANTI-PLATELETS
Aspirin
Clopidogrel
Prasugrel
Ticagrelor
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21
Q

Benign Prostatic Hyperplasia (BPH)

A

Doxazosin (A blocker)

Tamsulosin (A 1 blocker)

Finasteride (Anti-Androgens)

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22
Q

Acute Angina Pectoralis

A

GTN

ISMN

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23
Q

Cardiac Arrest

A 
SYMPATHOMIMETICS
Adrenaline
Dobutamine
Noradrenaline
Metaraminol
Isoprenaline
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24
Q

Cardiogenic Shock

A 
SYMPATHOMIMETICS
Adrenaline
Dobutamine
Noradrenaline
Metaraminol
Isoprenaline
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25
Q

Cardiovascular Disease Relief

A

ANTIPLATELETS
Aspirin
Clopidogrel

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26
Q

Anticoagulant Prophylaxis

A

ANTIPLATELET
Aspirin
Clopidogrel

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27
Q

Deep Vein Thrombosis

A 
ANTICOAGULANT
Warfarin (Vit Ki)
Apixiban (FXai)
Rivaroxaban (FXai)
Edoxaban (FXai)
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28
Q

Prophylaxis of Stroke from AF

A 
ANTICOAGULANT
Warfarin (Vit Ki)
Apixaban (FXai)
Edoxaban (FXai)
Rivaroxaban (FXai)
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29
Q

Prophylaxis of Venous Thromboembolism post-surgery

A

Dabigatran (Thrombin i)

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30
Q

Prophylaxis of Venous Thrombosis and PE

A 
ANTICOAGULANTS (Heparins)
Dalteparin
Tinzaparin
Enoxaparin
Unfractioned Heparin
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31
Q

MI

A

THROMBOLYTICS/FIBRINOLYTICS
Alteplase
Streptokinase
Urokinase

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32
Q

Ischaemic Stroke

A

THROMBOLYTICS/FIBRINOLYTICS
Alteplase
Streptokinase
Urokinase

ASPIRIN (Acute)

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33
Q

Hypercholesterolaemia

A

HMG-CoA Reductase i
Simvastatin
Atorvastatin
Rosuvastatin

PPAR-Alpha Activator
- Fenofibrate

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34
Q

CVD and Stroke Risk

A

HMG-CoA Reductase i
Simvastatin
Atorvastatin
Rosuvastatin

ANTI PLATELETS
Aspirin
Clopidogrel
Prasugrel
Ticagrelor
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35
Q

Ventricular and Supraventricular Arrythmias

A

Disopyramide (Class 1a)
Quinidine (Class 1a)

Amiodarone (Class 3)
Dronedarone (Class 3)
Sotalol (Class 3)

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36
Q

CPR

A

IV Lidocaine (Class 1b)

IV Amiodarone (Class 3)
IV Dronedarone (Class 3)
IV Sotalol (Class 3)
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37
Q

Paroxysmal AF

A

Flecaininde (Class 1c)

Propafenone (Class 1c)

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38
Q

Ventricular Ectopic Beats

A

Flecaininde (Class 1 c)

Propafenone (Class 1c)

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39
Q

Prophylaxis of Paroxysmal Atrial Tachycardia

A

Atenolol (Class 2)

Bisoprolol (Class 2)

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40
Q

Prophylaxis of Paroxysmal AF

A

Atenolol (Class 2)

Bisoprolol (Class 2)

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41
Q

Nodal Tachyarrythmias

A

Amiodarone (Class 3)
Dronedarone (Class 3)
Sotalol (Class 3)

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42
Q

Atrial Fibrilation

A

Amiodarone (Class 3)
Dronedaron (Class 3)
Sotalol (Class 3)

Digoxin (Cardiac Glycoside)

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43
Q

Supraventricular Tachycardia (Atria or AV node)

Atrial Flutter, AF, Paroxysmal SVT

A

Verapamil (Class 4)
Diltiazem (Class 4)

Adenosine

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44
Q

Arrythmias Generally

A

Digoxin ( Cardiac Glycoside)

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45
Q

Emergency Bradycardia

A

Atropine (Antimuscarininc)

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46
Q

Emergency Arrythmia

A

IV Magnesium Sulfate

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47
Q

Asthma Management

A

Salbutamol (B2-Ag)
Terbutaline (B2-Ag)
Salmeterol (B2-Ag)
Formoterol (B2-Ag)

Beclomethasone (Glucocorticoid)
Prednisolone (Glucocorticoid)
Hydrocortisone (Glucocorticoid)
Fluticasone (Glucocorticoid)

Montelukast (Leuk antag)
Zafirlukast (Leuk antag)

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48
Q

Reversible Airway Obstruction

A

Salbutamol (B2-Ag)
Terbutaline (B2-Ag)
Salmeterol (B2-Ag)
Formoterol (B2-Ag)

Theophylline (Methylxanthine)
Aminophylline (Methylxanthine)

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49
Q

Acute Asthma

A

Ipratropium (Antimusc)
Tiotropium (Antimusc)
Glycopyrronium (Antimusc)
Aclidinium (Antimusc)

Theophylline (MX)
Aminophylline (MX)

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50
Q

Bronchospasm in COPD

A

Ipratropium (Antimusc)
Tiotropium (Antimusc)
Glycopyrronium (Antimusc)
Aclindinium (Antimusc)

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51
Q

Allergic Rhinitis

A

Beclomethasone (Gluc)
Prednisolone (Gluc)
Hydrocortisone (Gluc)
Fluticasone (Gluc)

Montelukast (Leuk-Antag)
Zafirlukast (Leuk-Antag)

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52
Q

Parkinson’s Disease

A 
DOPAMINERGICS
Levodopa
Pramipexole
Ropinirole
Rotigotine

DOPA-DECARBOXYLASE INHIBITOR (increase levodopa)
Carbidopa
Benserazide

MAOI (increase dopamine)
Selegiline
Rasagaline

COMT INHIBITOR (increase dopamine)
Entacapone
Tolcapone

ANTICHOLINERGICS
Orphenadrine
Procyclidine
Trihexphenidyl

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53
Q

Muscle Rigidity

A

ANTICHOLINERGICS
Orphenadrine
Procyclidine
Trihexphenidyl

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54
Q

Side-effects of anti-psychotics

A

ANTICHOLINERGICS
Orphenadrine
Procyclidine
Trihexphenidyl

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55
Q

Huntingdon’s Chorea

A

DOPAMINE-DEPLETING DRUGS

Tetrabenazine

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56
Q

Depression

A 
SSRI
Sertraline
Fluoxetine
Citalopram
Paroxetine

RIMA
Moclobemide

TCA
Amitriptyline
Nortriptyline
Dosulepin

ATYPICAL
Venlafaxine
Reboxetine
Buproprion
Agomelatine
Mirtazepine
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57
Q

Generalised Anxiety Disorder

A 
SSRI
Sertraline
Fluoxetine
Citalopram
Paroxetine
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58
Q

Schizophrenia

A

Antipsychotics 1st Generation

  • Chlorpromazine
  • Haloperidol

Antipsychotics 2nd Generation

  • Olanzapine
  • Risperidone
  • Quetiapine
  • Clozapine
  • Amisulpride
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59
Q

Bipolar

A

Lithium Carbonate

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60
Q

Alzheimer’s Disease

A

CHOLINESTERASE INHIBITORS
Donepezil
Galantamine
Rivastigmine

NMDA RECEPTOR ANTAGONIST
Memantine

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61
Q

Mild to Moderate Dementia

A

CHOLINESTERASE INHIBITORS
Donepezil
Galantamine
Rivastigmine

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62
Q

Moderate to Severe Dementia

A

NMDA RECEPTOR ANTAGONIST

Memantine

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63
Q

Anxiety and Related Disorders

A

ANXIOLYTICS
Buspirone

BENZODIAZEPINES
Lorazepam
Midazolam
Diazepam
Zolpidem
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64
Q

Insomnia

A

Zopiclone (Non-benzo hypnotic)

65
Q

Epilepsy

A 
ANTI-EPILEPTICS
Sodium Valproate
Lamotrigine
Carbemazepine
Ethosuximide
Topiramate
Levetiracetam
Phenytoin
BENZODIAZEPINES
Lorazepam
Midazolam
Diazepam
Zolpidem

BARBITURATES
Phenobarbitone
Pentobarbitone
Primidone

66
Q

Acute Seizures

A 
BENZODIAZEPINES
Lorazepam
Midazolam
Diazepam
Zolpidem

BARBITURATES
Phenobarbitone
Pentobarbitone
Primidone

67
Q

Reversal of Benzodiazepine Sedation

A

Flumazenil

68
Q

Mild-Moderate Pain

A

Paracetamol (weak analgesic)

Codeine (opioid)
Dihydrocodeine (opioid)

Naproxen (NSAID)
Ibuprofen (NSAID)
Diclofenac (NSAID)

Etoricoxib (COX2)
Celecoxib (COX2)

69
Q

Pyrexia

A

Paracetamol

70
Q

Inflammation

A

Naproxen (NSAID)
Ibuprofen (NSAID)
Diclofenac (NSAID)

Etoricoxib (COX2)
Celecoxib (COX2)

71
Q

Severe Pain

A 
Morphine (opioid)
Diamorphine (opioid)
Pethidine (opioid)
Fentanyl (opioid)
Oxycodone
Remifentanil
72
Q

Moderate to Severe Pain

A

Buprenorphine
Pentazocine
Tramadol

73
Q

Opiate Overdose

A

Naloxone

Naltrexone

74
Q

Respiratory Depression

A

Naloxone

Naltrexone

75
Q

Opiate Addiction

A

Methadone

Buprenorphine

76
Q

Neuropathic Pain

A

Gabapentin
Pregabalin
Amitriptyline

77
Q

Analgesia During Childbirth

A

Nitrous Oxide + Oxygen

78
Q

Induction of anaesthesia throughout major surgery

A 
GENERAL ANAESTHETICS
Propofol
Isoflurane
Sevoflurane
Ketamine
79
Q

Local Anaesthesia

A

Lidocaine
Bupivacaine
Levobupivacaine

80
Q

Tracheal Intubation and mechanical ventilation during surgery

A 
NEUROMUSCULAR BLOCKERS
Atracurium besilate
Vecuronium
Suxamethonium
Rocuronium
81
Q

Immediate reversal of NMB to reduce post-operative pulmonary complications

A

Sugammadex (Reversing Neuromuscular Block)

82
Q

Myasthenia Gravis

A

Neostigmine (Reversing Neuromuscular block)

83
Q

Maintaining sedation and relaxed muscle tone

A

Temazepam (BDZ)
Zolpidem

Dexmedetomidine (a-2-ag)

Alfentanil (opioid)
Fentanil
Remifentanil

84
Q

Nausea and Vomiting

A

Cyclizine (H1 receptor blockade)

Domperidone (D2 receptor blockade)
Metoclopramide (D2 receptor blockade)

Ondansetron (5-HT3 receptor block)

85
Q

Respiratory Infection (Bacterial)

A

Penicillins (Beta Lactam)

  • Amoxicillin
  • Co-Amoxiclav
  • Piperacillin-Tazobactam
  • Flucloxacillin
  • Phenoxymethylpenicillin
86
Q

Pneumonia (Bacterial)

A

Penicillins (Beta Lactam)

  • Amoxicillin
  • Co-amoxicillin
  • Piperacillin-Tazobactam
  • Flucloxacillin
  • Phenomethylpenicillin

Macrolide Antibiotic

  • Erthromycin
  • Azithromycin
87
Q

H. Pylori

A

Penicillins (Beta Lactam)

  • Amoxicillin
  • Co-amoxiclav
  • Piperacillin-Tazobactam
  • Phenoxymethylpenicillin
  • Flucloxacillin
88
Q

Bacterial Meningitis

A

Carbapenems (Beta Lactam)
- Meropenem

Cephalosporins (Beta Lactam)
- Ceftriaxone

89
Q

Hospital-Acquired Septicaemia

A

Carbapenems (Beta Lactam)

- Meropenem

90
Q

Gram-negative infections

A

Cephalosporins (Beta Lactam)

- Ceftriaxone

91
Q

UTI

A

Antifolate Antibiotic
- Trimethoprim

Nitrofuran
- Nitrofurantoin

92
Q

Bacterial Respiratory Tract Infection

A

Fluoroquinolones

- Ciprofloxacin

93
Q

Community Acquired Pneumonia

A

Tetracycline Antibiotic

- Doxycycline

94
Q

Ophthalmic Infection

A

Aminoglycoside

- Gentamycin

95
Q

C. Difficile Infection

A

Glycopeptide

- Vancomycin

96
Q

Anaerobic Bacterial Infection: Leg ulcers, Pressure sores

A

Nitroimidazole (anti-anaerobe)

- Metronidazole

97
Q

Tuberculosis

A

Antituberculosis Drugs (used in combination)

  • Isoniazid (inhib of bac wall synth)
  • Ethambutol (inhib of bac wall synth)
  • Rifampicin (inhib of mycobac RNA synth)
  • Pyrazinamide
98
Q

Hepatitis B and C

A

Therapeuric Cytokines

- Interferon Alpha (activate immune response)

99
Q

Herpes simplex infection

A

DNA Polymerase Inhibitors (virus rep block)

  • Aciclovir
  • Ganciclovir
100
Q

Influenza Viral Infection

A

Neuraminidase Inhibitors

- Oseltamivir

101
Q

Hepatitis C and RSV

A 
Nucleoside Analogue (disrupt viral RNA synth)
- Ribavirin
102
Q

HIV Infection

A

Nucleoside reverse transcriptase inhibitor

  • Tenofovir
  • Nevirapine

Non-nucleoside reverse transcriptase inhibitors
- Efavirenz

Viral Protease inhibitor

  • Lopinavir
  • Ritonavir

Viral Entry Inhibitor
- Maraviroc

Integrase Inhibitor
- Dolutegravir

Viral fusion inhibitor
- Enfuviritide

103
Q

Candida Infection

A

Anti-fungal

  • Fluconazole
  • Clotrimazole
104
Q

Type 1 Diabetes Mellitus

A 
Insulin Glargine (long)
Insulin Linspro (rapid)
Insulin Aspart (short)
105
Q

Type 2 Diabetes Mellitus

A 
Insulin Glargine (long)
Insulin Linspro (rapid)
Insulin Aspart (short)

GLP-1 Agonist

  • Exenatide
  • Liraglutide

SGLT-2 Inhibitor

  • Dapigaflozin
  • Canagliflozin

Oral Biguanide - Metformin

  • increases insulin sensitivity
  • inhibits hepatic gluconeogenesis

Sulphonylurea - Gliclazide
- Stimulates pancreatic insulin secretion

Thiazolidinedione - Pioglitazone
- increases insulin sensitivity in muscle and adipose

GLP-1 agonist - Exenatide
- incretin (blood glucose reducer) hormone analogue

DPP-4 inhibitor - Sitagliptin
- Reduces inactivation of incretins

Lipase inhib - Orlistat
- Inhib of GI fat uptake

106
Q

Obesity

A

Lipase Inhib - Orlistat

107
Q

Hypothyroidism

A 
Levothyroxine Sodium (T4)
Liothyronine Sodium (T3)
108
Q

Rheumatoid Arthritis

A

Antifolate Antiproliferative
- Methotrexate

Thiopurine Antiproliferative

  • Azathioprine
  • 6-Mercaptopurine

Antimetabolite Antiproliferative
- Leflunomide

Cytokine Modulators

  • Adalimumab
  • Etanercept
  • Infliximab

Aminosalicylates

  • Sulfasalazine
  • Mesalazine
109
Q

Crohn’s Disease

A

Thiopurine Antiproliferative

  • Azathioprine
  • 6-Mercaptopurine

Cytokine Modulators TNF-Alpha block

  • Adalimumab
  • Etanercept
  • Infliximab

Aminosalicylates

  • Sulfasalazine
  • Mesalazine
110
Q

Hormonal Contraception

A

Oral combination pill
- Desogestrel and Ethinylestradiol

Oral mini-pill Progesterone only

  • Desogestrel
  • Levonorgestrel (emergency)

Implants
- Etonogestrel

Progesterone Receptor Modulator (Emergency)
- Ulipristal

111
Q

PCOS

A

Oral combination pill

- Desogestrel and Ethinylestradiol

112
Q

Menopause

A

HRT

  • Estradiol
  • Noresthisterone
  • Medroxyprogesterone
113
Q

Delay in Labour

A

Induction of Labour
- Dinoprostone

Augmentation Agents
- Oxytocin

114
Q

Termination of Pregnancy

A

Antiprogestogen/Prostaglandin

- Mifepristone with Misoprostol

115
Q

Menorrhagia

A

Antifibrinolytic

- Tranexamic Acid

116
Q

Dysmenorrhoea

A

NSAID

- Mefenamic Acid

117
Q

Benign Prostatic Hyperplasia

A

Alpha-1-blocker
- Tamsulosin

Anti-Androgen
- Finasteride

118
Q

Urinary Retention

A

Alpha-1-Blocker

- Tamsulosin

119
Q

Overactive Bladder

A

Antispasmodic (AntiACh)

  • Oxybutynin
  • Solifenacin
  • Tolterodine

Beta-3-Agonist
- Mirabegron

120
Q

Hay Fever

A

Anti-Histamine

- Chlorphenamine

121
Q

Urticaria

A

Anti-Histamine

- Chlorphenamine

122
Q

Suppression of Inflammatory Diseases (Crohn’s, RA)

A

Glucocorticoids

  • Prednisolone
  • Hydrocortisone
  • Dexamethasone
123
Q

Solid Organ Transplantation

A

Calcineurin Inhibitor

  • Cyclosporin
  • Tacrolimus

Inosine Monophosphate Dehydrogenase Inhibitor
- Mycophenolate

124
Q

Eczema (topical)

A

Calcineurin Inhibitor

  • Cyclosporin
  • Tacrolimus
125
Q

Broad spectrum of Malignancies

A

Classical Alkylating Agent
- Cyclophosphamide

Taxanes

  • Paclitaxel
  • Docetaxel

Vinca Alkaloids

  • Vincristine
  • Vinblastine

Antifolates
- Methotrexate

Antipyramidines

  • Fluorouracil
  • Cytarabine

Antipurines

  • Mercaptopurine
  • Thioguanine

Anthracycline Antibiotics
- Doxorubicin

126
Q

Early Breast Cancer

A

Antineoplastic MAB

- Trastuzumab

127
Q

Folicular Lymphoma

A

Antineoplastic MAB

- Rituximab

128
Q

Non-Hodgkin’s Lymphoma

A

Antineoplastic MAB

- Rituximab

129
Q

Melanoma

A

Antineoplastic MAB

- Nivolumab

130
Q

Breast Cancer

A

SERM

- Tamoxifen

131
Q

Prostate Cancer

A

LHRH receptor agonist

- Goserelin

132
Q

Osteoporosis

A

Therapeutic Calcitonin Hormone

Bisphosophates

  • Alendronate
  • Pamidronate
  • Risedronate

Denosumab (MAB)

133
Q

Hypercalcaemia

A

Therapeutic Calcitonin Hormone

Bisphosphonates

  • Alendronate
  • Pamidronate
  • Risedronate
134
Q

Hypocalcaemia

A

Drugs for Hypocalcaemia

  • IV calcium gluconate
  • Vitamin D
  • PTH
135
Q

Bone Loss

A

Drugs for Hypocalcaemia

  • IV calcium gluconate
  • Vitamin D
  • PTH
136
Q

Vitamin D Deficiency

A

Vitamin D

  • Colecalciferol
  • Calcitriol
  • 1,25-dihydroxyvitamin D
137
Q

Prevention of Bone Fractures

A

Selective oestrogen receptor modulator (SERM) for osteoporosis
- Raloxifene

138
Q

Iron-Deficient Anaemia

A

Ferrous Sulphate

139
Q

Folate-deficient anaemia

A

Folic Acid

140
Q

Pernicious Anaemia

A

Hydroxocobalamin (B12 enzyme co-factor)

141
Q

Paracetamol Overdose

A

N-Acetylcysteine

142
Q

Severe Alcohol Misuse

A

GABA Activators
Chlordiazepoxide
Clomethiazole
Acamprosate

143
Q

Migraine

A

Sumatriptan (onset)

Topiramate (prophylaxis)

144
Q

Bone and Joint Infections

A

Lincosamide - Clindamycin

145
Q

Threadworm

A

Mebendazole (Anti-helmintic)

146
Q

Hookworm

A

Mebendazole (Anti-helmintic)

147
Q

Scabies

A

Permethrin (Pyrethrine) Topical

148
Q

Elevated Triglycerides

A

PPAR-Alpha Activator

- Fenofibrate

149
Q

Diabetes Insipidus

A

Desmopressin

150
Q

Hyperthyroidism

A

Anti-Thyroids

  • Propylthiouracil
  • Carbimazole
151
Q

Acute Gout

A

Colchicine

152
Q

Gout Prophylaxis

A

Xanthine Oxidase inhibitors

  • Allopurinol
  • Febuxostat
153
Q

Chronic Gout

A

Indometacin (NSAID)

154
Q

Neutropaenia

A

Synthetic G-CSF

- Filgrastim

155
Q

Severe Acne

A

Retinoids

  • Acitretin
  • Isotretinoin
156
Q

Psoriasis

A

Retinoids

  • Acitretin
  • Isotretinoin
157
Q

Myeloma

A

Immunomodulator

- Lenolidamide

158
Q

Follicular Lymphoma

A

Antineoplastic mab

- Rituximab

Drugs List Phase 3 (5 decks)

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