INCREASED DIRECT BILIRUBIN Flashcards
prehepatic jaundice
Hemolytic anemia and G-6-PD deficiency
bilirubin transport deficit; hepatic
unconjugated
Gilbert’s Syndrome
conjugation deficit; hepatic
unconjugated
Criggler-Najjar Syndrome
conjugation inhibitor ;
hepatic unconjugated
LUCEY- DRISCOLL SYNDROME
liver; hepatic jaundice
Hepatocellular disease
List of INCREASED INDIRECT BILIRUBIN
- Biliary obstruction (gall stones)
- Pancreatic (head) cancer
- Alcoholic and viral hepatitis
- Biliary atresia
- Hepatocellular disease
INCREASED INDIRECT BILIRUBIN
INCREASE IB
PREHEPATIC
INCREASED INDIRECT BILIRUBIN
INCREASE IB, DB
HEPATIC
INCREASED INDIRECT BILIRUBIN
INCEASE DB
POST
Colorless end product of bilirubin metabolism that is oxidized by intestinal flora to urobilin
UROBILINOGEN
UROBILINOGEN
Collection of sample
avoid light exposure
UROBILINOGEN
decrease in
urobilinogen; B2 can’t go to intestine and cant
oxidize to urobilinogen.
COMPLE BILIARY OBSTRUCTION
UROBILINOGEN
from the liver will go to intestine (converted to
urobilinogen by intestinal flora.
B2
UROBILINOGEN
2-hr freshly collected urine or freshly
collected stool
Specimen
UROBILINOGEN
Method
EHRLICH’S METHOD- p DABA (pdimethulaminobenzaldehyde_
