Incontinence/Pelvic Prolapse Flashcards

1
Q

Two basic types of incontinence

A

stress: leak w/ increase in intra-abdominal P
urge: dysfunctional neural system, bladder contraction

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2
Q

Alpha-1 receptors are found where in lower urinary tract

A

sm muscle of urethra

keeps urethral tone

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3
Q

Beta-2 and 3 receptors are found where in lower urinary tract

A

detrusor wall

allows for relaxation of bladder dome

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4
Q

Parasympathetic/sympathetic cause bladder contraction

A

parasympathetic

M3 receptors

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5
Q

Which parasympathetic receptors are stimulatory in bladder

A

M3 receptors

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6
Q

Common medication class used to treat urge incontinence

A

anti-cholinergics

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7
Q

Most common side effect of anti-cholinergics

A

dry mouth

salivary glands also have muscarinic receptors

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8
Q

Type of muscle and innervation of
internal urethral sphincter
external urethral sphincter

A

internal: sm muscle w/ M3 receptors
external: sk muscle w/ somatic innervation

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9
Q

Control of continence normally by what age

A

2 y/o

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10
Q

Describe
stress incontinence
urge incontinence

A

stress: small leakage w/ increase in intra-abdominal pressure
urge: leak large amounts of urine w/ urgency before accident
often appears mixed clinically

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11
Q

Probably most common type of incontinence

A

mix between stress and urge incontinence

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12
Q

What type of incontinence do men typically get 2˚ to BPH

A

overflow incontinence
causes dribbling when bladder gets too full
inability to empty bladder b/c of urethral compression

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13
Q

Why does menopause lead to urinary incontinence

A

decrease in estrogen
causes decrease in CT surrounding urethra
internal and external sphincters cannot close as tightly
intra-abdominal pressure may overcome urethral sphincter pressure and cause stress incontinence

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14
Q

Functional incontinence

A

inability to actually get to toilet

2˚ to injury or inability to ambulate

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15
Q

Post-void residual volume

A

used to see if how much urinary retention after voiding

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16
Q

Best lifestyle treatment for stress incontinence

A

Kegels

17
Q

Best lifestyle treatment for urge incontinence

A

scheduled emptying/bladder retraining

takes 2-3 months

18
Q

Probably best bet treating incontinence in post-menopausal women

A

intravaginal estrogen

not systemic-that may make it worse

19
Q

Most common anticholinergic

A

oxybutyin

20
Q

Oxybutyin
MOA
TU

A

MOA: non-selective anticholinergic
TU: urge incontinence

21
Q

Mirabegron
MOA
TU

A

MOA: beta-2 and -3 agonist
TU: urge incontinence

22
Q

Major risk factor for pelvic prolapse

A

chronic cough-ie from smoking