In Class Notes (2/28 and 3/3) Flashcards
A drug binds to where the neurotransmitters bind to the receptor. Exact same binding location:
Direct Binding
Does not bind where the neurotransmitter would bind:
Indirect Binding
Facilitates or helps the postsynaptic effects:
Agonist
Impairs or hurts the postsynaptic effects:
Antagonist
An indirect antagonist that inhibits the overall effects of neurotransmitters by blocking the Ca++ channel from opening when bound:
PCP (Phencyclidine)
A drug that binds to the same site as PCP and also blocks NMDA receptors as an indirect antagonist:
Ketamine
Ionotropic Cl- channels with fast inhibitory effects:
GABA(a) Receptors
Metabotropic K+ receptors with inhibitory effects:
GABA(b) Receptors
Blocking something inhibitory results in excitatory effects:
Blocking GABA Receptors
Inhibits the reuptake of serotonin, increasing serotonin levels in the synapse:
Selective Serotonin Reuptake Inhibitors (SSRIs)
A chemical “ligand” interacts with _______ ________ embedded in a sensory receptor cell, initiating the taste process:
Receptor Proteins
These proteins in taste function similarly to porous ionotropic and metabotropic receptors:
Receptors Proteins
When salt (NaCl) dissolves in saliva, it separates into ___ and ____, with Na+ acting as a tastant for salt receptor cells
Na+; Cl-
____ interacts with an ion channel embedded within the membrane of a salt receptor cell, contributing to taste perception:
Na+
Is both an amino acid neurotransmitter and a tastant ligand:
Glutamate
The voltage of the inside of the receptor:
Receptor Potential
When an external chemical causes an electrical response in a receptor:
Transduction
A type of neuron that carries sensory information and has a single process that branches into two:
Afferent Neuron (Pseudounipolar Neuron)
