Important Doses

Question 1

Celecoxib

Answer 1

Celecoxib 200 mg QD ( < 400 mg QD for CVD) for less than 5 days

Question 2

Tramadol

Answer 2

Tramadol 25-50 mg TDS (Max: 400 mg/day)

Question 3

Colchicine

Answer 3

Colchicine 1.5 mg/day
One-off: 1.0 mg then 0.5 mg 1 hour later
Alternative: 0.5 mg TDS until symptoms resolve

Question 4

Allopurinol

Answer 4

Allopurinol 100-300 mg/day (Max: 800 mg/day): 50-100 mg increase every 2-8 wks

Question 5

Febuxostat

Answer 5

Febuxostat 40-80 mg QD after 2-4 wks

Question 6

Probenecid

Answer 6

Probenecid 250 mg BD for 1 week, 500 mg BD. Titrate every 4 weeks

Question 7

Methotrexate

Answer 7

Methotrexate 7.5 mg/week + Folic acid 5 mg/week

Question 8

Prednisolone

Answer 8

Prednisolone 5-7.5 mg QD

Question 9

Sulfasalazine

Answer 9

Sulfasalazine 500 mg QD or BD, maintenance at 1000 mg/day

Question 10

Hydroxychloroquine

Answer 10

Hydroxychloroquine 200-400 mg/day

Question 11

Leflunomide

Answer 11

Leflunomide 100 mg/day for 3 days (Maintenance: 20 mg/day)

Question 12

Alendronate

Answer 12

Alendronate 70 mg/week

Question 13

Risedronate

Answer 13

Risedronate 35 mg/week

Question 14

Zoledronic acid

Answer 14

Zoledronic acid 5 mg IV Infusion 30 min every year

Question 15

Denosumab

Answer 15

Denosumab SQ every 6 months

Question 16

Raloxifene

Answer 16

Raloxifene 60 mg QD (PO)

Question 17

Teriparatide

Answer 17

Teriparatide 20µg QD (SQ) for 24 months