Immunology-Serology-Blood Banking Flashcards
ISBT 001
ABO Blood Group
Antibody in M. pneumoniae infection
Anti-I
Antibody found only in blacks
Anti-U
Major advantage of gel technology
Standardization
What are perfluorocarbons
Blood susbtitute
Antibody diversity
Susumu Tonegawa
Classical pathway was named so because
It was the first pathway to be studied
Mantoux test determines what hypersensitivity
Type IV
Most common immunodeficiency
Selective IgA deficiency
Adsorbed by beef / ox erythrocytes
Infectious mononucleosis antibody
Duffy phenotype associated with P. knowlesi
Fy6
Rh phenotype frequently seen in Asians
R1 (DCe)
MMR vaccine deferral
4 weeks (ARC) or 8 weeks (NVBSP)
C3 convertase in the classical pathway
C4b2a
Jet-like pulsating bright red blood
Puncture of artery
Blood component for Rosenthal syndrome
FFP
Phenotype of Rh null
—/—
1C increase in temperature
Febrile nonhemolytic transfusion reaction
Specimen in DAT
EDTA (or citrated) whole blood
Discovered structure of antibodies
Rodney Porter and Gerald Edelman
The name Lutheran is derived from
Donor named Luteran
Blood group linked to C4
Chido / Rodgers
Anticoagulant discovered in 1943
ACD
Shelf life of RBCs in SAG-M
42 days
Cells form a pellet (gel technology)
Negative
Anti-microsomal antibody
Hashimoto’s thyroiditis
Fluorescent pattern of anti-Sm
Speckled
HLA-B27
Ankylosing spondylitis
Antibody is attached to carrier
Reverse passive agglutination
Uses bacteria a inert particles
Coagglutination
Reactive qualitative VDRL. What’s next
Quantitative VDRL
Developed by Venereal Disease Research Laboratory
VDRL
What are LAK cells
NK cells + IL-2
Proteins in Western blot ate blotted on
Nitrocellulose paper
Blocking test immunofluorescence assay
Inhibition immunofluorescent assay
She killed people due to typhoid fever
Mary Mallon
Year of T cell receptor gene discovered
1984
Template for PCR
dsDNA
Rh phenotype with highest D Ag sites
D–
1st discovered human retrovirus
HTLV-1
Chromosomal number for ABO
9q
T cells are found in _____ of the spleen
Periarteriolar sheath
Anticoagulant in lymphotoxicity assay
Heparin
Macrophage found in the liver
Kupffer cell
Last stage of HIV infection
Full blown AIDS
Resembles mast cells
Basophil
IgG subclass that cannot fix complement
IgG 4
Detects allergen-specific IgE
RAST
Boyden chamber assay is a test for
Chemotaxis
Temperature for complement activation
56C
Membrane attack complex
C5b6789
Bond that connects IgM monomers
Disulfide bond
Most complex blood group system
Rh
Number of H antigens currently identified
4
Brilliant apple green fluorescent grading
4+
Dolichos biflorus aggregates what cell (s)
A(1) and A(1)B cells
Automated method that uses microwells in BB
Solid phase
The only FDA approved rejuvenating solution
Rejuvesol
% of glycerol used in slow freezing technology
40%
Removes cross-reactive reaction with other treponemes
Reiter strain
Primary antibody type seen in H. pylori infection
IgG
“T” in the TORCH synonym stands for
Toxoplasmosis
Radioactive source used for irradiation
Cesium-137, Cobalt-60, X-ray
1st step when transfusion reaction occurs
Stop the transfusion
Who developed the gel technology
Dr. Yves Lapierre
Normal biota means
Normal flora
Major site of antibody production
Spleen
Remedy for prozone phenomenon
Serum dilution
High incidence antigens are called
Public antigens
Who can bleed blood donors
RMT, RN, MD
Newest blood group system
RHAG
Total protein required for plasmapheresis
6.0 g/dL or more
Typhoid attenuated vaccine deferral
2 weeks
Color of bovine serum albumin
Colorless
Patient has no IgA but has anti-IgA
Anaphylactic reaction
Cell that stimulates B cells to plasma cells
Helper T cell
Absence of DAF leads to
PNH
Antigen determinant; antibody binding site
Epitope
APR that increase 1000x during acute inflammation
CRP
Anti-CCP is associated with
Rheumatoid arthritis
Antibody identification in serum of Mrs. Kellaher
Anti-K
“I” in the I blood group stands for
Individuality
Antibody 1st described in serum of Mrs. Jay
Anti-PP1, Pk (Anti-Tja)
Double negative thymocytes are
Immature T cells
Microscope in lymphocytotoxicity a.
Phase-contrast
Mitogen activating both B and T cells
Pokeweed mitogen
Alzheimers disease is associated to what protein
Neural thread protein
Rose-Waaler test is used to detect
Rheumatoid Factor (RF)
Cryoprecipitate + thrombin
Fibrin glue
Cut-off for BNP in TACO
1.5
Shelf life of blood bag stored in ice box
8 hours
Miscarriage in 4th moth of pregnancy
No deferral
Antibody with refractile mf agglutination reaction
Anti-Sd(a)
New confirmatory test for HIV in Philippines
rHIVda
Antibody titer in Candida infection
1:8
If only anti-RBS is (+), it indicates
Hepatitis B immunization
Recessive genes are expressed if
In homozygous form (e.g. OO ➡️ O Ag)
Sedimentation coefficient of IgM
19s
Absence of B cells and all Ig’s
Bruton’s agammaglobulinemia
Steps in PCR
Denaturation
Annealing
Extension
Serum to RBC ratio (drops) in X-maturation
2:1
Blood factors in Rh0 individuals
Rh(0) hr’ hr’’
Lewis phenotype in newborns
Le (a-b-)
SDP contain therapeutic equivalent of _____ RDP
4 to 6
Why is plasma not preferred in BB
Anticoagulant interferes with complement
Found in patient dial. formaid-sterile equipment
Anti-N
Who introduced citrate-dextrose anticoagulant
Rous and Turner
“En” in the En(a-) stands for
Envelope
Anti-Jk(a): enhanced of destryoyed
Enhanced
Located on the anion exchange molecule
Diego antigens
