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Quizzer > Immunology-Serology-Blood Banking > Flashcards

Immunology-Serology-Blood Banking Flashcards

1
Q

ISBT 001

A

ABO Blood Group

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2
Q

Antibody in M. pneumoniae infection

A

Anti-I

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3
Q

Antibody found only in blacks

A

Anti-U

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4
Q

Major advantage of gel technology

A

Standardization

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5
Q

What are perfluorocarbons

A

Blood susbtitute

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6
Q

Antibody diversity

A

Susumu Tonegawa

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7
Q

Classical pathway was named so because

A

It was the first pathway to be studied

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8
Q

Mantoux test determines what hypersensitivity

A

Type IV

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9
Q

Most common immunodeficiency

A

Selective IgA deficiency

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10
Q

Adsorbed by beef / ox erythrocytes

A

Infectious mononucleosis antibody

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11
Q

Duffy phenotype associated with P. knowlesi

A

Fy6

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12
Q

Rh phenotype frequently seen in Asians

A

R1 (DCe)

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13
Q

MMR vaccine deferral

A

4 weeks (ARC) or 8 weeks (NVBSP)

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14
Q

C3 convertase in the classical pathway

A

C4b2a

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15
Q

Jet-like pulsating bright red blood

A

Puncture of artery

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16
Q

Blood component for Rosenthal syndrome

A

FFP

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17
Q

Phenotype of Rh null

A

—/—

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18
Q

1C increase in temperature

A

Febrile nonhemolytic transfusion reaction

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19
Q

Specimen in DAT

A

EDTA (or citrated) whole blood

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20
Q

Discovered structure of antibodies

A

Rodney Porter and Gerald Edelman

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21
Q

The name Lutheran is derived from

A

Donor named Luteran

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22
Q

Blood group linked to C4

A

Chido / Rodgers

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23
Q

Anticoagulant discovered in 1943

A

ACD

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24
Q

Shelf life of RBCs in SAG-M

A

42 days

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25
Q

Cells form a pellet (gel technology)

A

Negative

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26
Q

Anti-microsomal antibody

A

Hashimoto’s thyroiditis

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27
Q

Fluorescent pattern of anti-Sm

A

Speckled

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28
Q

HLA-B27

A

Ankylosing spondylitis

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29
Q

Antibody is attached to carrier

A

Reverse passive agglutination

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30
Q

Uses bacteria a inert particles

A

Coagglutination

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31
Q

Reactive qualitative VDRL. What’s next

A

Quantitative VDRL

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32
Q

Developed by Venereal Disease Research Laboratory

A

VDRL

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33
Q

What are LAK cells

A

NK cells + IL-2

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34
Q

Proteins in Western blot ate blotted on

A

Nitrocellulose paper

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35
Q

Blocking test immunofluorescence assay

A

Inhibition immunofluorescent assay

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36
Q

She killed people due to typhoid fever

A

Mary Mallon

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37
Q

Year of T cell receptor gene discovered

A

1984

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38
Q

Template for PCR

A

dsDNA

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39
Q

Rh phenotype with highest D Ag sites

A

D–

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40
Q

1st discovered human retrovirus

A

HTLV-1

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41
Q

Chromosomal number for ABO

A

9q

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42
Q

T cells are found in _____ of the spleen

A

Periarteriolar sheath

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43
Q

Anticoagulant in lymphotoxicity assay

A

Heparin

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44
Q

Macrophage found in the liver

A

Kupffer cell

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45
Q

Last stage of HIV infection

A

Full blown AIDS

46
Q

Resembles mast cells

A

Basophil

47
Q

IgG subclass that cannot fix complement

A

IgG 4

48
Q

Detects allergen-specific IgE

A

RAST

49
Q

Boyden chamber assay is a test for

A

Chemotaxis

50
Q

Temperature for complement activation

A

56C

51
Q

Membrane attack complex

A

C5b6789

52
Q

Bond that connects IgM monomers

A

Disulfide bond

53
Q

Most complex blood group system

A

Rh

54
Q

Number of H antigens currently identified

A

4

55
Q

Brilliant apple green fluorescent grading

A

4+

56
Q

Dolichos biflorus aggregates what cell (s)

A

A(1) and A(1)B cells

57
Q

Automated method that uses microwells in BB

A

Solid phase

58
Q

The only FDA approved rejuvenating solution

A

Rejuvesol

59
Q

% of glycerol used in slow freezing technology

A

40%

60
Q

Removes cross-reactive reaction with other treponemes

A

Reiter strain

61
Q

Primary antibody type seen in H. pylori infection

A

IgG

62
Q

“T” in the TORCH synonym stands for

A

Toxoplasmosis

63
Q

Radioactive source used for irradiation

A

Cesium-137, Cobalt-60, X-ray

64
Q

1st step when transfusion reaction occurs

A

Stop the transfusion

65
Q

Who developed the gel technology

A

Dr. Yves Lapierre

66
Q

Normal biota means

A

Normal flora

67
Q

Major site of antibody production

A

Spleen

68
Q

Remedy for prozone phenomenon

A

Serum dilution

69
Q

High incidence antigens are called

A

Public antigens

70
Q

Who can bleed blood donors

A

RMT, RN, MD

71
Q

Newest blood group system

A

RHAG

72
Q

Total protein required for plasmapheresis

A

6.0 g/dL or more

73
Q

Typhoid attenuated vaccine deferral

A

2 weeks

74
Q

Color of bovine serum albumin

A

Colorless

75
Q

Patient has no IgA but has anti-IgA

A

Anaphylactic reaction

76
Q

Cell that stimulates B cells to plasma cells

A

Helper T cell

77
Q

Absence of DAF leads to

A

PNH

78
Q

Antigen determinant; antibody binding site

A

Epitope

79
Q

APR that increase 1000x during acute inflammation

A

CRP

80
Q

Anti-CCP is associated with

A

Rheumatoid arthritis

81
Q

Antibody identification in serum of Mrs. Kellaher

A

Anti-K

82
Q

“I” in the I blood group stands for

A

Individuality

83
Q

Antibody 1st described in serum of Mrs. Jay

A

Anti-PP1, Pk (Anti-Tja)

84
Q

Double negative thymocytes are

A

Immature T cells

85
Q

Microscope in lymphocytotoxicity a.

A

Phase-contrast

86
Q

Mitogen activating both B and T cells

A

Pokeweed mitogen

87
Q

Alzheimers disease is associated to what protein

A

Neural thread protein

88
Q

Rose-Waaler test is used to detect

A

Rheumatoid Factor (RF)

89
Q

Cryoprecipitate + thrombin

A

Fibrin glue

90
Q

Cut-off for BNP in TACO

A

1.5

91
Q

Shelf life of blood bag stored in ice box

A

8 hours

92
Q

Miscarriage in 4th moth of pregnancy

A

No deferral

93
Q

Antibody with refractile mf agglutination reaction

A

Anti-Sd(a)

94
Q

New confirmatory test for HIV in Philippines

A

rHIVda

95
Q

Antibody titer in Candida infection

A

1:8

96
Q

If only anti-RBS is (+), it indicates

A

Hepatitis B immunization

97
Q

Recessive genes are expressed if

A

In homozygous form (e.g. OO ➡️ O Ag)

98
Q

Sedimentation coefficient of IgM

A

19s

99
Q

Absence of B cells and all Ig’s

A

Bruton’s agammaglobulinemia

100
Q

Steps in PCR

A

Denaturation
Annealing
Extension

101
Q

Serum to RBC ratio (drops) in X-maturation

A

2:1

102
Q

Blood factors in Rh0 individuals

A

Rh(0) hr’ hr’’

103
Q

Lewis phenotype in newborns

A

Le (a-b-)

104
Q

SDP contain therapeutic equivalent of _____ RDP

A

4 to 6

105
Q

Why is plasma not preferred in BB

A

Anticoagulant interferes with complement

106
Q

Found in patient dial. formaid-sterile equipment

A

Anti-N

107
Q

Who introduced citrate-dextrose anticoagulant

A

Rous and Turner

108
Q

“En” in the En(a-) stands for

A

Envelope

109
Q

Anti-Jk(a): enhanced of destryoyed

A

Enhanced

110
Q

Located on the anion exchange molecule

A

Diego antigens

Quizzer (6 decks)

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