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Quizzer > Hematology > Flashcards

Hematology Flashcards

1
Q

A medical technologist was performing erythrocyte morphology evaluation and observed 10 to 20 stomatocytes per oil immersion field. This is graded as

A

2+

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2
Q

Codocytes graded as 3+

A

Greater than 20 per field

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3
Q

Codocytes: 41 per OIF

A

3+

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4
Q

A microscopist saw at least 5-10 acanthocytes per oil immersion field. The medical technologist should report it as

A

2+

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5
Q

A peripheral blood smear was reported to have 2+ schistocytes. How many of the said poikilocyte is expected to be seen per OIF

A

5-10

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6
Q

Twelve (12) RBCs with basophilic stippling were seen on a blood smear. How do you report this finding

A

Positive

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7
Q

Pathway that provides reduced glutathione

A

Hexose monophosphate shunt / PPP

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8
Q

WBC count is <3.0, what is the dilution

A

1:10

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9
Q

Length of capillary tube

A

7.0-7.5 cm (70-75 mm)

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10
Q

Zone that maintains the platelet shape

A

Sol-gel-zone

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11
Q

5-15 degrees light scatter

A

High angle forward scatter

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12
Q

Stomatocyte grading of 2+

A

10-20/ OIF (or 11-20/field)

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13
Q

> 11% of cells are polychromatophilic

A

4+

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14
Q

Test for CGD

A

NBT dye test

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15
Q

Positive instrumental errors

A

Bubbles on the sample
Extraneous electrical current
Aperture plugs

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16
Q

“Wheel spoke” chromatin pattern

A

Basophilic normoblast

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17
Q

Platelet structure that contains alpha granules

A

Organelle zone

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18
Q

Quantity of reagent used in PT

A

200 ul (0.2 mL)

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19
Q

Principle of Coulter and Sysmex

A

Electrical impedance

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20
Q

Seepage of blood into large areas

A

Ecchymosis

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21
Q

Leukemia associated with DIC

A

M3

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22
Q

Rouleaux grading aggregates of 3-4 RBC

A

1+

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23
Q

Thin rim of hemoglobin

A

4+

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24
Q

Negative instrumental error

A

Excessive lysing of RBCs

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25
Q

Derived from platelet histogram

A

MPV and PDW

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26
Q

Normal anticoagulant in the body

A

Heparin

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27
Q

Wavelength in cyanmethemoglobin method

A

540 nm

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28
Q

(+) Philadelphia chromosome

A

Good prognosis

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29
Q

Visual detection of clot formation

A

Tilt tube

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30
Q

Improper setting of aperture current/threshold

A

Positive or negative error

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31
Q

Large, homogenous lymphocytes

A

L3

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32
Q

Size of blood drop for smear preparation

A

2-3 mm

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33
Q

Acute monoblastic leukemia

A

M5

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34
Q

2 zeta 2 gamma, what hemoglobin

A

Portland

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35
Q

> 20 codocytes per field

A

3+

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36
Q

Platelet estimated of 100,000-149,000 / uL

A

Slight decrease

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37
Q

Also known as congenital pure red cell aplasia

A

Diamond-Blackfan anemia

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38
Q

Alder-Reilly granules are PAS

A

Positive

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39
Q

Sticking of platelets to one another

A

Platelet aggregation

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40
Q

Cytochemical stain (+) in L1, L2, and M6

A

PAS

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41
Q

Ohm’s law

A

Voltage = current x resistance

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42
Q

Adjusted Drabkin’s reagent platelet count is

A

> 700 x 10^9/L

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43
Q

Abnormal iron granulocyte in RBCs in Wright stain

A

Pappenheimer bodies

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44
Q

Monocyte that is (+) with PAS stain

A

Gaucher cell

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45
Q

Undergoes 1st stage of endomitosis

A

LD-CFU-Meg

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46
Q

In uremia, platelet function is impaired due to

A

Nitric oxide (NO)

47
Q

Maturation time of eosinophils

A

3.5 days

48
Q

Standard dilution for platelet count

A

1:100

49
Q

Normal template bleeding time

A

6-10 minutes

50
Q

Smear slide angle if patient has polycythemia vera

A

25 degrees

51
Q

Cell cycle: DNA replication occurs

A

Synthesis (S) stage

52
Q

Objective used for snow plow effect

A

LPO

53
Q

Principle involved in dithionite test

A

Reduction

54
Q

Largest cell in the bone marrow

A

Megakaryocyte

55
Q

Components of flow cytometer

A

Computer
Optics
Fluidics
Electronics

56
Q

Test for quantitating Factor VIII inhibitor

A

Bethesda assay

57
Q

Allow platelets to settle in hemocytometer for

A

15 minutes

58
Q

Allow WBCs to settle in hemocytometer for

A

10 minutes

59
Q

If buffer is too acidic, RBCs are

A

Too pink

60
Q

Dithionite is a screening test for

A

Hemoglobin S

61
Q

Solid tumor counterpart of ALL

A

Lymphoma (poorly differentiated)

62
Q

Relationship between ESR and RBC mass

A

Directly proportional

63
Q

Dacryocytes are associated with

A

Myelofibrosis

64
Q

Increase PT and APTT, NC by normal plasma

A

Circulating (lupus) anticoagulant

65
Q

MPV is measured at what period

A

1-3 hours after blood collection

66
Q

If platelet count is low, MPV is

A

High

67
Q

Microhematocrit tubes should be read within

A

10 minutes after centrifugation

68
Q

Erythroid cell with “checkerboard” nucleus

A

Polychromatophilic normoblast

69
Q

Tertiary granules are 1st produced in

A

Metamyelocyte

70
Q

LAP activity on CML

A

Decreased

71
Q

Also known as “Plasma thromboplastin component”

A

Factor IX

72
Q

Major cause of death in sickle cell anemia

A

Bacterial infection

73
Q

Dendritic cell originated from

A

Common lymphoid progenitor cell

74
Q

Reticulated platelets are seen in

A

Immune thrombocytopenic purpura

75
Q

Acute Basophilic Leukemia

A

M8

76
Q

Pince-nez nucleus

A

Heterozygous Pelger-Huet anomaly

77
Q

Needle gauge for pediatric phlebotomy

A

Gauge 23

78
Q

Trapped plasma increase hematocrit by

A

1-3%

79
Q

Acute erythroleukemia

A

M6

80
Q

Zone than contains mitochondria

A

Organelle zone

81
Q

PT and APTT result in polycythemia

A

Both prolonged

82
Q

ESR reference sample not returned to RT

A

Increased

83
Q

ESR in congestive heart failure

A

Decreased

84
Q

Cell cycle: cell has stopped dividing

A

G0

85
Q

INR to prevent deep vein thrombosis

A

2 to 3

86
Q

Neutrophil stays in the PB for how long

A

7 hours

87
Q

PT and APTT specimen must be centrifuged within

A

1 hour

88
Q

Total area of Levy chamber

A

9 mm^2

89
Q

Adjust Drabkin’s reagent if WBC count is

A

> 20 x 10^6/L

90
Q

Anticoagulant for OFT

A

Heparin

91
Q

alpha-2 beta-2 6 glucose to lysine

A

Hemoglobin C

92
Q

Test: (+) Holly leaf appearance

A

Metabisulfite test

93
Q

Phagocytic cell (s) containing lysozyme

A

Neutrophils and monocytes

94
Q

2 cells pass thru orifice, counted as 1

A

Coincidence

95
Q

Effect of platelet satellitism on platelet count

A

False-decrease

96
Q

Size threshold range for platelets

A

2-20 fL

97
Q

Plasma thromboplastin component

A

Factor IX

98
Q

MK with MODERATE condensed chromatin

A

MK-II

99
Q

Solid tumor counterpart of stem cell leukemia

A

Lymphoma, undifferentiated

100
Q

Solid plasma tumor counterpart of plasma cell leukemia

A

Myeloma

101
Q

PPE for enteric isolation

A

Gloves, gown

102
Q

Granule absent in Hermansky-Pudlak

A

Dense granules

103
Q

Effect of megakaryocyte fragments in WBC count

A

False-increase

104
Q

Effect of old specimen on MCV

A

False-increase

105
Q

Effect of old specimen on platelet count

A

False-decrease

106
Q

Effect of old specimen on MPV

A

False-increase

107
Q

Effect of cold agglutinins on MCHC

A

False-increase

108
Q

Effect of lipemia on hemoglobin determination

A

False-increase

109
Q

Individual globules of immunoglobulins in plasma cells

A

Russell bodies

110
Q

M:E ratio of 10:1 is often seen in

A

Leukemia

111
Q

Severe increase in abnormal erythrocyte in MF

A

3+

112
Q

What are anulocytes

A

RBCs with thin rim of hemoglobin

113
Q

During 1st hour, MPV of EDTA specimen increases by

A

20%

Quizzer (6 decks)

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