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Quizzer > Clinical Chemistry > Flashcards

Clinical Chemistry Flashcards

1
Q

Abrupt change in the mean

A

Shift

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2
Q

6 values continue to increase/decrease

A

Trend

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3
Q

Vertical line (y-axis)

A

Dependent variable

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4
Q

Major apolipoprotein of chylomicrons

A

Apo B48

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5
Q

Transferin, hemopexin, complement

A

Beta globulins

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6
Q

UV region

A

<400 nm

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7
Q

Most concentrated NPN

A

Urea

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8
Q

Enzyme category of 5’-nucleotidase

A

Hydrolase

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9
Q

CK-MB will begin to rise after

A

4-6 hours

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10
Q

Metal with high affinity to keratin

A

Arsenic

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11
Q

Determine difference between SD of 2 groups of data

A

F-test

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12
Q

Treatment for various seizure disorders

A

Carbamazepine

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13
Q

Emphysema causes what acid-base disorder

A

Respiratory acidosis

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14
Q

Used for measuring pH and pCO2

A

Potentiometry

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15
Q

Effect of increased glucose to sodium

A

Decreased sodium

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16
Q

Conversion factor of BUN to UREA

A

2.14

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17
Q

Increased growth hormone in children

A

Gigantism

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18
Q

Blood alcohol level of 0.35-0.50%

A

Coma and possible death

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19
Q

Reverse metabolism for LDH

A

Wrobleuski La Due

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20
Q

Substrate in Bowers and McComb (ALP)

A

p-nitrophenylphosphate (PNPP)

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21
Q

Vertical position when not in use

A

Horizontal centrifuge

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22
Q

Lipoprotein with the least density

A

Chylomicrons

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23
Q

Beta-gamma bridging

A

Liver cirrhosis

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24
Q

% Blood alcohol: Impaired consciousness

A

0.27-0.40

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25
Q

BMI of underweight

A

<18.5 kg/m^2

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26
Q

Enzyme classification of G6PD

A

Oxidoreductase

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27
Q

Depends on substrate concentration

A

First order kinetics

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28
Q

Phosphomolybdate reagent

A

Folin-Wu

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29
Q

Uses common reaction vessel

A

Continuous flow analyzer

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30
Q

Middle or midpoint value

A

Median

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31
Q

10% bleach inactivates HBV in

A

10 minutes

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32
Q

Copper-binding glycoprotein

A

Ceruloplasmin

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33
Q

Odor of bitter almonds

A

Cyanide poisoning

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34
Q

Confirmatory test for acromegaly

A

Glucose-suppression - OGTT (75g)

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35
Q

Sample used in external QC

A

Blind sample

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36
Q

Very FAR from a set of control values

A

Outlier

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37
Q

Methylenedioxymethampethamine

A

Ecstasy

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38
Q

Common specimen used for POCT

A

Capillary blood

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39
Q

CTAD anticoagulant is used for

A

Coagulation studies

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40
Q

Part of “glucose tolerance factor”

A

Chromium

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41
Q

8 values on one side of the mean

A

8x

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42
Q

Enzyme classification of aldolase

A

Lyase

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43
Q

Most heat-labile isoenzyme

A

Bone

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44
Q

Ideal fasting time for lipid studies

A

12 hours

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45
Q

Highest CK activity is seen in

A

Duchenne’s muscular dystrophy

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46
Q

Non protein molecule for enzyme activity

A

Cofactor

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47
Q

E + S = ES = E + P

A

Enzyme catalytic reaction

48
Q

Enzyme increased in chronic alcoholism

A

GGT

49
Q

Hypernatremia when serum Na is

A

> 145 mmol/L

50
Q

Electrode used for potassium (K)

A

Valinomycin-based electrode

51
Q

Generally used reagent water type

A

Type 2

52
Q

Conversion factor for cholesterol

A

0.026

53
Q

BMI of overweight individuals

A

25 - 29.9

54
Q

3 step method for cholesterol determination

A

Abell-Kendal

55
Q

Relative concentration of a solution

A

Dilution

56
Q

Known as the “master gland”

A

Pituitary gland

57
Q

Enzyme used for rape investigation

A

ACP

58
Q

Cause of relative hyperproteinemia

A

Dehydration

59
Q

Kernicterus is accumulation of bilirubin in the

A

Brain tissues

60
Q

Compare previous specimen from recent result

A

Delta check

61
Q

Most common cause of hyperkalemia

A

Impaired renal excretion

62
Q

Reverse method for CK

A

Oliver-Rosalki

63
Q

Zona glomerulosa produces

A

Mineralocorticoids (e.g. Aldosterone)

64
Q

Vitamin C deficiency leads to

A

Scurvy

65
Q

Critical level for hyperkalemia

A

> 6.5 mEq/L

66
Q

Most potent androgen

A

Testosterone/dihydrotestosterone

67
Q

Marked hyperkalemia may lead to

A

Cardiac arrest

68
Q

Odor of garlic breath toxicity

A

Arsenic toxicity

69
Q

Reference method for measurement of urea

A

IDMS

70
Q

Increased cortisol, increased ACTH

A

Cushing’s disease

71
Q

Electrolytes for neuromuscular excitability

A

K, Ca, Mg

72
Q

Theophylline and theobromine are

A

Bronchodilators

73
Q

Panic value for high bicarbonate

A

> 40 mEq/L

74
Q

Screening test for acromegaly

A

Somatomedin-C

75
Q

Jaundice is evident when bilirubin is

A

> 2 mg/dL

76
Q

Non-destructive technique for lipoprotein particles deficiency

A

Nuclear magnetic resonance spectrophotometry (NMRS)

77
Q

A/G ratio in multiple myeloma and cirrhosis

A

Low

78
Q

Method for measurement of metanephrine and normetanephrine

A

Pisano method

79
Q

Main cause of QC shift

A

Improper calibration of instrument

80
Q

Legally intoxicated blood alcohol level

A

100 mg/dL or higher

81
Q

It uses fluorophore-labeled thyroxine

A

FPIA (fluorescence polarization immunoassay)

82
Q

Vitamin B3 deficiency may lead to

A

Pellagra

83
Q

Effect of amino acids on GH secretion

A

Increased

84
Q

Transportation of drug from administration site to blood

A

Adsorption

85
Q

Effect of thrombocytosis on serum potassium

A

Increased

86
Q

Electrolyte for myocardial rhythm and contraction

A

K, Ca, Mg

87
Q

Effect of hypercalcemia on AG

A

Decreased

88
Q

Electrolyte maintaining electroneutrality

A

Chloride

89
Q

Enzyme classification of cholineesterase

A

Hydrolase

90
Q

BUN and creatinine are significantly increased if GFR is

A

Decreased by at least 50%

91
Q

Overzealous treatment of DM may lead to

A

Hypoglycemia

92
Q

Lipoprotein found in obstructive jaundice, LCAT deficiency

A

Lipoprotein x

93
Q

LFT for hepatocellular damage and necrosis

A

Serum AST levels (Widmann)

94
Q

Unit prefix for 1 million (1x10^6)

A

Mega

95
Q

Cause of hyperglycemia during pregnancy

A

Hormonal changes

96
Q

Why is plasma not preferred for SPE

A

Due to pseudo beta-gamma bridging effect

97
Q

Peak absorbance of uric acid happens at what wavelength

A

285 nm

98
Q

Reflects lowest drug concentration in blood

A

Trough concentration

99
Q

Temperature of analyzer (random/systematic)

A

Random error

100
Q

Uses luminol and luminometer for T4

A

Chemiluminiscence

101
Q

3M urea inhibits what ALP isoenzyme

A

Bone ALP

102
Q

Most prominent benzodiazepine

A

Valium

103
Q

Is pentazocine natural or synthetic

A

Synthetic

104
Q

Numerator in H-H equation reflects

A

Kidney (bicarbonate reabsorption)

105
Q

Alpha 1,4-glucosidase deficiency

A

Pompe disease

106
Q

To establish DM symptoms, RBS should be

A

> 200 mg/dL

107
Q

Conversion factor of ammonia

A

0.587

108
Q

Major advantage of centrifugal analysis

A

Batch analysis

109
Q

Borderline high for TAG

A

150-199 mg/dL

110
Q

Marker for bone resorption

A

Cross-linked C telopeptide

111
Q

10-fold increase in AMG is seen in

A

Nephrotic syndrome

112
Q

Effect of salicylate poisoning on AG

A

Increased

113
Q

1st responder to stress within seconds

A

Catecholamines

114
Q

IC iron transporter: int surface to inside cell

A

DMT-1

115
Q

Electrolyte, BUN, crea, osmolality done. Next?

A

Determine osmolal gap

Quizzer (6 decks)

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