Immunology Flashcards
What are the physical/ chemical barriers that pathogens must cross to invade the body?
Skin
Mucosa–> Respt tract, GI tract, Genitcal tract/ urinary system
Chemical barriers–> Stomach acid, Lysozyme (sweart and tears)
What is the initial response to a pathogen invading tissue?
Complement system activation
What is the complement system?
Part of the immune system that enhances the ability of antibodies and phagocytic cells to clear microbes and damaged cells, promote inflammation and attack pathogen’s cell membrane.
What is the next step after the complement system has been activated?
Macrophages recognise pathogens and activate hte innate immune system
What happens after the innate immune system has been activated?
Dendritic cells pick up antigens and activate the specific immune system
What does ‘Baso’ mean?
Foundation
What does ‘Blast’ mean?
Immature cells
What does ‘cyte’ mean?
cell
What does ‘Eosin’ mean?
Red coloured
What does ‘Haemo’ mean?
Blood
What does ‘Karyo’ mean?
Nucleus
What does ‘Kine’ mean?
Motion
What does ‘Myelo’ mean?
Bone marrow
What does ‘Neutro’ mean?
Neutral
What does ‘phage’ mean?
eat
What does ‘Phil’ mean?
Attraction
What does ‘Poietic’ mean?
Creative
What does ‘Potent’ mean?
Potential
What does ‘Pro’ mean?
Moving forward
What does ‘Reticulo’ mean?
Net like
What is the first phase of a blood cell?
Pluripotent Haematopoietic stem cell
What are the 3 types of undifferentiated heamatopoeitic stem cells?
Myeloid Stem Cells
Lymphoid Stem Cells
Dendritic Cells
What do Myeloid Stem Cells become?
Megakaryocytes–> Platelets
Reticulocytes–> RBC’s
Promyelocytes
What do Megakaryocytes produce?
Platelets