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W18-Immunity and immunology > Immunology > Flashcards

Immunology Flashcards

1
Q

What are the 2 types of immunity

A
  • Innate immunity

- Adaptive immunity

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2
Q

What makes up adaptive immunity

A

Tcells

B cells

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3
Q

What make up innate immunity

A

Physical barriers

Blood borne cells

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4
Q

Name the blood borne cells

A 
Neutrophils 
Macrophages 
Basophils 
Eosinophils 
Natural Killer cells
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5
Q

Describe the speed of innate and adaptive immunity

A 
innate= fast (hours/days)
Adaptive= slow (days/weeks)
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6
Q

Describe the duration of innate and adaptive immunity

A 
innate= short (days)
adaptive= long (months/years)
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7
Q

List the cells of the innate immune system

A 
Neutrophil
Eosinophil
Basophil
NK cell
Mast cells 
Antigen presenting cells
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8
Q

List the cells that make up the adaptive immune system

A

Lymphocytes (T, B,memory)
Plasma cells
Antigen presenting cells

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9
Q

List examples of antigen presenting cells

A

Monocyte
Macrophage
B lymphocyte
Dendritic cell

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10
Q

Describe Neutrophils

A
  • Short lived
  • First leukocyte migrating to infection site
  • Are phagocytic
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11
Q

Describe Monocyte/ Macrophage

A
  • Phagocytes
  • Monocyte= circulates in blood and differentiate into macrophage after migrating into tissues
  • Macrophages= act as antigen presenting cells
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12
Q

Describe Eosinophil

A
  • Circulates in blood

- Protective role against parasites

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13
Q

Describe Basophil

A

Circulates in blood

Response to allergens (releases histamine)

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14
Q

Describe Mast cells

A
  • Found within tissue, role in inflammation

- Response to allergens (releases histamine)

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15
Q

Describe NK cells

A

Natural Killer cells
Is a cytotoxic lymphocyte
Role in destruction of virus infected cells

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16
Q

Describe Dendritic cells

A
  • antigen presenting cell

many subsets according to their tissue location

17
Q

Describe B cells

A

Express membrane bound receptors/ antibodies
involved in adaptive immunity
differentiate into plasma cells(release antibodies) or memory B-cells

18
Q

Describe T cells

A
  • involved in adaptive immune response
  • Recognise antigen displayed by major histocompatibility complex
  • Range of subsets including T helper cells, cytotoxic Tcells
19
Q

What is a Major Histocompatibility complex (MHC)

A
  • Glycoproteins expressed on cell surface that present peptide chains to other cells
  • There are 2 classes (MHC class 1, MHC class 2)
20
Q

Describe MHC class 1

A

expressed on surface of most cells

21
Q

Describe MHC class 2

A
  • primarily on antigen presenting cells

W18-Immunity and immunology (7 decks)

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