Immunology

Question 1

What are the CD1 (a,b,c) molecules markers of?

Answer 1

Dendritic antigen-presenting cells (Langerhans cells, dermal dendritic cells).

Question 2

Where is the T-cell receptor/CD3 complex expressed?

Answer 2

Only on the surface of mature T-cells.

Question 3

What cells express CD5 antigens?

Answer 3

Almost all mature T-cells & a minor subset of B cells (B1).

Question 4

What cells express CD8 antigens?

Answer 4

MHC class 1-restricted T supressor/cytotoxic cells.

Question 5

Which cells express CD14 antigens?

Answer 5

Monocytes, subsets of macrophages & subsets of B-cells.

Question 6

What is CD14 a receptor for?

Answer 6

LPS (endotoxin) & LPS binding protein complexes.

Question 7

What cells express CD21?

Answer 7

Mature B cells.

Question 8

What processes are CD44 antigens involved in?

Answer 8

Lymphocyte trafficking & activation.

Question 9

What is CD44 a receptor for?

Answer 9

CD44 is a broadly expressed adhesion receptor for hyaluronate on many cells.

Question 10

What family is CD45?

Answer 10

The leukocyte common antigen family.