Immunology Flashcards
most important co-stimulator
B7 (CD80) CD 28 (from T cell)
delayed separation of umbilical cord
phagocytic deficiency
no oral thrush
CMI test is negative
T cell enumeration is abnormal
T lymphocyte deficiency
cellular and combined PID
poorest prognosis
most common well-defined immunodeficiency disorder
selective IgA deficiency
defect in the class-switch recombination (CSR)
hyper-IgM syndrome
duncan disease
X-linked lymphoproliferative disease
velopharyngeal incompetence, feeding difficulties, speech delay
Di George Syndrome
recurrent S. aureus abscesses
Candidiasis with hyper IgE syndrome
most common form of SCID
X-linked SCID
difference of SCID and combined immunodeficiency
SCID - no T cell
Combined - not absent T cell function
bare lymphocyte syndrome, CD8
MHC class I deficiency
cryptosporidiasis andenteroviral infections, CD4 low
MHC class II
triad of WAS
bleeding
infection
eczema
most characteristic finding at diagnosis in WAS
thrombocytopenia
small platelets
earliest manifestation in bleeding of WAS
petechiae
bruises
most common defect in CHS
truncated LYST protein
most common rheumatic disease in children
juvenile idiopathic arthritis
most common subtype of JIA
olidoarthritis
initial symptom in pediatric systemic sclerosis
reynaud phenomenon
classic triphasic sequence of reynaud phenomenon
blanching
cyanosis
erythema
