Immunology Flashcards
most important co-stimulator
B7 (CD80) CD 28 (from T cell)
delayed separation of umbilical cord
phagocytic deficiency
no oral thrush
CMI test is negative
T cell enumeration is abnormal
T lymphocyte deficiency
cellular and combined PID
poorest prognosis
most common well-defined immunodeficiency disorder
selective IgA deficiency
defect in the class-switch recombination (CSR)
hyper-IgM syndrome
duncan disease
X-linked lymphoproliferative disease
velopharyngeal incompetence, feeding difficulties, speech delay
Di George Syndrome
recurrent S. aureus abscesses
Candidiasis with hyper IgE syndrome
most common form of SCID
X-linked SCID
difference of SCID and combined immunodeficiency
SCID - no T cell
Combined - not absent T cell function
bare lymphocyte syndrome, CD8
MHC class I deficiency
cryptosporidiasis andenteroviral infections, CD4 low
MHC class II
triad of WAS
bleeding
infection
eczema
most characteristic finding at diagnosis in WAS
thrombocytopenia
small platelets
