Allergy 2 Flashcards
most common chronic relapsing skin disease seen in infancy and childhood
atopic dermatitis
hallmark of atopic dermatitis
severely dry skin
predisposed to development of allergic rhinitis and/or asthma later in childhood
atopic march
a structural protein in the epidermis, and its breakdown products are critical to skin barrier formation
filaggrin
cardinal features of atopic dermatitis
intense pruritus - especially at night
cutaneous reactivity
adolescents who present with an eczematous dermatitis but no history of childhood eczema, respiratory allergy, or atopic family history may have allergic ______
contact dermatitis
gene mutations in filaggrin gene family have been identified in up to ___% of patients with severe AD
50%
urticaria treatment epinephrine
provides rapid relief of acute, severe urticaria/ angioedema but is seldom required
0.3mL IM
the diagnosis is almost always clinical in what type of allergy
food allergy
IgE mediated food allergies develop in may be sensitized by food allergens penetrating the GIT barrier
class 1 food allergens
food allergens that are partially homologous to plant pollens penetrating the respiratory tract
class 2 food allergens
serious allergic reaction that is rapid in onset and may cause death
anaphylaxis
atopic dermatitis major features
pruritus
dermatitis with typical distribution
chronic or relapsing
history of atopy
2 types of allergen immunotherapy
SCIT - subcutaneous immunotherapy
SLIT - sublingual immunotherapy
most common cause of rashes
viral infection
