Immunological Dx Flashcards
Scleroderma & 3 main comps
Rheumatic, conn tissue dx associated w impaired immune responses; Vascular: Raynauds, constant recurrent restriction of BVs=pulm HTN & decreased esophageal motility. Fibrotic: thick/burning skin, restrictive lung disease. Autoimm: B-cell prod antibodies > genetic/environmentallty induced; most often women
Limited Scleroderma
Skin involvement w good prognosis & linear scleroderma=bands of thicker skin w good prognosis
Systemic Scleroderma
Of internal organs=life threatening; CREST syndrome w good prognosis: Calcinosis, Raynauds, Esophageal dysfun; Sclerodactyly of fingers/toes & Telangiectasis or red spots covering hands/feet/forearms/face/hips
Tx for Raynauds (Scleroderma)
Dress in layers - clothing modification (fingers/toes); Biofeedback - guided imagery to focus on distal circulation; Edu on skin inspection; Activity mod to prevent trauma to fingers/toes
Tx for Contractures rel to Scleroderma
Splint at optimal resting length for hands/wrists to slow development; Silicone gel in plams; Electrical/mechanical muffled vibration to stim rapidly adapting A-type nerve fibers & decrease burning sensation
Gen tx for Scleroderma
Nasal O for pulmonary artery probs, diet mods for Gi probs, cessation of exercise if myositis, protective gloves(cotton, insulated, mildly compressive) if fibrosis skin probs
AIDs: Acquired Immunodeficiency Disease
Acquired through unprotected sex/blood or body fluids.
HIV: Human Immunodeficiency Disease
Retrovirus (DNA); Attacks lymphatic system (immunity system) - T cells/CD4 attack body
4 Stages of HIV Infection
Acute: flu-like. Asymptomatic: HIV replicated and affects imm system but does not show signs other than blood abnormalities. Symptomatic: signs/symptoms appear. Advanced: severely compromised immunity; CD5 (T cell) levels drop
HIV Symptoms
Enlarged lymph nodes, fatigue, weight loss/malabsorption of nutrients, fever, diarrhea, decreased act tol, neurolog impairment: cog, affective, sensory, ADL impairments, myelopathy, peripheral neuropathy, visual impairment
Hep A/B
Viral infections. A= contaminated seafood/protective imm possible. B/C/Others= body or blood borne exposure/protective imm possible for B. HC workers are most susceptible to B. Fever, fatigue, decreased act tol & cirrhosis (liver degen)
Methicillin-Resistant Staphylococcus Aureus: MRSA
Usually mild infections (pimps/boils) > can be more serious including in surgical wounds. Can be local or systemic thru bloodstream affecting lungs or urinary tract. Risks: Weakened immune system, hosp confinement, close quarter living, direct contact (sports) or secondary (towels). Resists most antiboticis
MRSA Signs/Symptoms
Red/swelling/pain at wound, drainage, fever, skin abscess, chest pain, cough, fatigue, head/mus ache, rash, SOB - chance of reoccurring in future
Tx for Acute Hosp of Imm System Disorders
Early mobilization, preservation of function, positioning, psychological/emo support, prevent LT disability
Tx for In Pt Rehab of Imm System Disorders
Eval/restoration of fx’al abilities: ADL, IADL, econ, work simp, restoration of activity/ex tol, achievement /maintenance of QOL, role adjustment intervention, plan comm re-integ