IMMUNOLOGIC DISEASES (WEGENER GRANULOMATOSIS / GRANULOMATOSIS WITH POLYANGIITIS) Flashcards

1
Q

CONCEPT

A

RARE CHRONIC IMMUNE-BASED INFLAMMATORY NECROTIZING VASCULITIS

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2
Q

CAUSE

A

UNKNOWN

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3
Q

SYMPTOMES

A

NECROTIZING GRANULOMATOUS LESONS RESPIRATORY TRACT/NECROTIZING GLOMERULONEPHRITIS/SYSTEMIC VASCULITIS SMALL ARTERIES/VEINS

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4
Q

ORALLY

A
  • STRAWBERRY GINGIVITIS
  • ORAL ULCERATIONS (ANY MUCOSA SURFACE)
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5
Q

DIAGNOSIS

A

COMBINATION CLINICAL PRESENTATION/MICROSCOPIC FINDING OF NECROTIZING AND GRANULOMATOUS VASCULITIS

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6
Q

LABORATORY MARKERS

A

ANTINEUTROPHIL CYTOPLASMATIC ANTIBODIES (cANCAS)/ANTINEUTROPHIL PERINUCLEAR ANTIBODIES (pANCAS)

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7
Q

TREATMENT

A

CORTICOSTEROIDS (PREDNISONE)/CYCLOPHOSPHAMIDE

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