Immunodeficiency Disorders Flashcards
Recurrent infections with fungi, viruses or protozoa
T-cell deficiency
Very low levels of all immunoglobulins. Virtual absence of b-cells due to tyrosine kinase muation
Bruton’s agammagkobulinemia/ xlinked aggamaglobulinemia
Treatment for brutons aggamaglobulinemia
Pooled gamma globulin
Recurrent bacterial sinus and lung infections
Selective IgA deficiency
B-cell deficiencies
Bruton,s/ XLA
IgA deficiency
Profound deficit of T-cells
Di george syndrome
Treatment for di george syndrom
Transplant of fetal thymus
Di george syndrome
CATCH 22
cardiac defect TOF abnormal facies Thymic aplasia Cleft palate Hypocalcemia 22q11.2 chromosomal deletion
Chrinic granulomatous candidiasis
T cell deficiency treatment
Azole antifungals
Mutation in WASP gene
Wiskot-aldrich syndrome
Tx: bone marrow transplant
Ataxia, telangiectasia, IgA deficiency
Ataxia-telangiectasia
Phagocyte disorders
Chronic granulomatous disease
Chediak-higashi syndrome
Leukocyte adhesion deficiency
Failure of phagolysisomal fusion
Chediak higashi syndrome
Treatment for chefiak higashi syndrome
Antibiotics
Deficiency in c5-c9. Inability to fir membrane-attack complexes
Terminal complement deficiency
